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Effects of propofol anesthesia induction on the relationship between arterial blood pressure and heart rate
- Source :
- EMBC, Scopus-Elsevier
- Publication Year :
- 2012
- Publisher :
- IEEE, 2012.
-
Abstract
- This paper presents the analysis of autonomic nervous system (ANS) control of heart rate (HR) and of cardiac baroreflex sensitivity (BRS) in patients undergoing general anesthesia for major surgery through spectral analysis techniques and with the Granger causality approach that take into account the causal relationships between HR and arterial blood pressure (ABP) variability. Propofol produced a general decrease in ABP due to its vasodilatory effects, a reduction in BRS, while HR remained unaltered with respect to baseline values before induction of anesthesia. The bivariate model suggests that the feedback pathway of cardiac baroreflex could be blunted by propofol induced anesthesia and that the feedforward pathway could be unaffected by anesthesia.
- Subjects :
- Settore MED/41 - Anestesiologia
Hemodynamics
Vasodilation
anesthesia
male
middle aged
Heart rate
heart rate
medicine
Propofol anesthesia
In patient
humans
Propofol
arterial pressure
aged
female
business.industry
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
Autonomic nervous system
Blood pressure
Anesthesia
Settore ING-INF/06 - Bioingegneria Elettronica e Informatica
business
medicine.drug
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
- Accession number :
- edsair.doi.dedup.....0dda73d6264be7e9ffe2d95a2c528dae