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Left behind: The potential impact of CFTR modulators on racial and ethnic disparities in cystic fibrosis
- Source :
- Paediatr Respir Rev
- Publication Year :
- 2022
- Publisher :
- eScholarship, University of California, 2022.
-
Abstract
- The advent of CFTR modulators, a genomic specific medication, revolutionized the treatment of CF for many patients. However, given that these therapeutics were only developed for specific CFTR mutations, not all people with CF have access to such disease-modifying drugs. Racial and ethnic minority groups are less likely to have CFTR mutations that are approved for CFTR modulators. This exclusion has the potential to widen existing health disparities.
- Subjects :
- Pulmonary and Respiratory Medicine
Race
Cystic Fibrosis
Respiratory System
Cystic Fibrosis Transmembrane Conductance Regulator
Cardiorespiratory Medicine and Haematology
CFTR modulators
Article
Congenital
Rare Diseases
Orphan Drug
Good Health and Well Being
Clinical Research
5.1 Pharmaceuticals
Pediatrics, Perinatology and Child Health
Mutation
Ethnicity
Humans
Development of treatments and therapeutic interventions
Lung
Minority Groups
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Paediatr Respir Rev
- Accession number :
- edsair.doi.dedup.....0e2cfc19a2395bdac395d8fe928d8958