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Additional file 6: of Evaluating in vivo efficacy – toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

Authors :
Johanna, Inez
Straetemans, Trudy
Heijhuurs, Sabine
Aarts-Riemens, Tineke
Norell, Håkan
Bongiovanni, Laura
Bruin, Alain De
Sebestyen, Zsolt
Kuball, Jürgen
Publication Year :
2019
Publisher :
figshare, 2019.

Abstract

Figure S4. Gating strategy for flow cytometry analysis of healthy hematopoietic compartments. A representative flow cytometry plot of murine peripheral blood. (A) Engraftment was determined by quantifying absolute cell number of viable huCD45+ of healthy stem cells; (B) Hematopoietic cellular compartments outgrowth were determined by quantifying absolute cell number for CD19+ B cells, CD3+ T cells, and CD14+ monocytes. Also, persistence of TEGs were determined by quantifying absolute cell number for γδTCR+ cells. (PPTX 225 kb)

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....0e80f2df453cc22b85214501a94c335e
Full Text :
https://doi.org/10.6084/m9.figshare.7850636.v1