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Incidence of anaphylactic reactions after propofol administration in dogs
- Source :
- The Journal of Veterinary Medical Science
- Publication Year :
- 2017
- Publisher :
- Japanese Society of Veterinary Science, 2017.
-
Abstract
- Propofol is an anesthetic agent suspended in an emulsion system that includes egg yolk lecithin and soybean oil, because of which, there is concern about the use of propofol in patients allergic to these substances. We examined the association between propofol administration and incidence of adverse events in dogs with allergy to egg yolk lecithin and soybean oil. On the basis of the findings of an allergen-specific immunoglobulin E (IgE) test, 14 dogs with high levels (high-IgE group) and 7 dogs with low levels (normal-IgE group) of IgE were selected. Following intravenous administration of propofol, the incidence of anaphylactic reactions and plasma histamine concentrations under general anesthesia maintained with isoflurane throughout surgery were compared between the two groups. The frequency of anaphylactic reactions and plasma histamine concentrations were compared by the chi-square test and Student t-test, respectively. The statistical significance for both tests was set at P
- Subjects :
- Male
Allergy
040301 veterinary sciences
Anesthesia, General
anesthesia
Immunoglobulin E
0403 veterinary science
03 medical and health sciences
chemistry.chemical_compound
Dogs
0302 clinical medicine
Lecithins
Animals
Hypnotics and Sedatives
Medicine
Dog Diseases
Egg Hypersensitivity
Adverse effect
Anaphylaxis
Propofol
Retrospective Studies
immunoglobulin-E
Full Paper
propofol-induced anaphylaxis
General Veterinary
biology
business.industry
Incidence
04 agricultural and veterinary sciences
Perioperative
medicine.disease
histamine
Soybean Oil
030228 respiratory system
chemistry
Isoflurane
Anesthesia
dog
biology.protein
Surgery
Female
business
Anesthetics, Intravenous
Histamine
medicine.drug
Subjects
Details
- ISSN :
- 13477439 and 09167250
- Volume :
- 79
- Database :
- OpenAIRE
- Journal :
- Journal of Veterinary Medical Science
- Accession number :
- edsair.doi.dedup.....0e8c31c9e9d68d658982fc209428d28f