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U-TEST, a simple decision support tool for the diagnosis of sarcopenia in orthopaedic patients: the Screening for People Suffering Sarcopenia in Orthopedic cohort of Kobe study (SPSS-OK)
- Source :
- The British journal of nutrition. 126(9)
- Publication Year :
- 2021
-
Abstract
- We aimed to develop and validate a new simple decision support tool (U-TEST) for diagnosis of sarcopenia in orthopaedic patients. We created seventeen candidate original questions to detect sarcopenia in orthopaedic patients with sarcopenia through expert opinions and a semi-structured interview. To derive a decision support tool, a logistic regression model with backward elimination was applied to select variables from the seventeen questions, age and underweight (BMI < 18·5 kg/m2). Sarcopenia was defined by Asian Working Group for Sarcopenia 2019 criteria. After assigning a score to each selected variable, the sum of scores was calculated. We evaluated the diagnostic performance of the new tool using a logistic regression model. A bootstrap technique was used for internal validation. Among a total of 1334 orthopaedic patients, sixty-five (4·9 %) patients were diagnosed with sarcopenia. We succeeded in developing a ‘U-TEST’ with scores ranging from 0 to 11 consisting of values for BMI (Underweight), age (Elderly) and two original questions (‘I can’t stand up from a chair without supporting myself with my arms’ (Strength) and ‘I feel that my arms and legs are thinner than they were in the past’ (Thin)). The AUC was 0·77 (95 % CI 0·71, 0·83). With the optimal cut-off set at 3 or greater based on Youden’s index, the sensitivity and the specificity were 76·1 and 63·6 %, respectively. In orthopaedic patients, our U-TEST scoring with two questions and two simple clinical variables can help to screen for sarcopenia.
- Subjects :
- medicine.medical_specialty
Sarcopenia
Medicine (miscellaneous)
Logistic regression
03 medical and health sciences
0302 clinical medicine
Thinness
medicine
Humans
Mass Screening
030212 general & internal medicine
Muscle Strength
Aged
Nutrition and Dietetics
business.industry
medicine.disease
Confidence interval
Cross-Sectional Studies
Orthopedics
Cohort
Orthopedic surgery
Mann–Whitney U test
Physical therapy
Underweight
medicine.symptom
business
human activities
Body mass index
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 14752662
- Volume :
- 126
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- The British journal of nutrition
- Accession number :
- edsair.doi.dedup.....0f03a76e0631080ffecafee2f09a37c4