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Epidemiology of intra-abdominal infection and sepsis in critically ill patients: 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project

Authors :
Blot
S. aEmail Author
Antonelli M. b
c Arvaniti
K. d Blot
K. a Creagh-Brown
B. e f
de Lange
D. g
De Waele
J. h Deschepper
M. i Dikmen
Y. j Dimopoulos
G. k Eckmann
C. l Francois
G. m Girardis
M. n Koulenti
D. o p
Labeau S. a
q Lipman
J. r s
Lipovestky F. t
Maseda E. u
Montravers P. v
w Mikstacki
A. x y
Paiva
J. -A. z
Pereyra
C. aa
Rello
J. ab
Timsit
J. -F. ac
ad Vogelaers
D. ae
Lamrous A.
Rezende-Neto J.
Cardenas Y.
Vymazal T.
Fjeldsoee-Nielsen H.
Kott M.
Kostoula A.
Javeri Y.
Einav S.
Makikado L. D. U.
Tomescu D.
Gritsan A.
Jovanovic B.
Venkatesan K.
Mirkovic T.
Creagh-Brown B.
Emmerich M.
Canale M.
Dietz L. S.
Ilutovich S.
Miñope J. T. S.
Silva R. B.
Montenegro M. A.
Martin P.
Saul P.
Chediack V.
Sutton G.
Couce R.
Balasini C.
Gonzalez S.
Lascar F. M.
Descotte E. J.
Gumiela N. S.
Pino C. A.
Cesio C.
Valgolio E.
Cunto E.
Dominguez C.
Nelson N. F.
Abegao E. M.
Pozo N. C.
Bianchi L.
Correger E.
Pastorino M. L.
Miyazaki E. A.
Grubissich N.
Garcia M.
Bonetto N.
Quevedo N. E.
Gomez C. D.
Queti F.
Estevarena L. G.
Fernandez R.
Santolaya I.
Grangeat S. H.
Doglia J.
Zakalik G.
Pellegrini C.
Lloria M. M.
Chacon M. E.
Fumale M.
Leguizamon M.
Hidalgo I. B.
Tiranti R. J.
Capponi P.
Tita A.
Cardonnet L.
Bettini L.
Ramos A.
Lovesio L.
Miranda E. M.
Farfan A. B.
Tolosa C.
Segura L.
Bellocchio A.
Alvarez B.
Manzur A.
Lujan R.
Fernandez N.
Scarone N.
Zazu A.
Groh C.
Fletcher J.
Smith J.
Azad R.
Chavan N.
Wong H.
Kol M.
Campbell L.
Starr T.
Roberts B.
Wibrow B.
Warhurst T.
Chinthamuneedi M.
Ferney B. B.
Simon M.
De Backer
D. Wittebole
De Bels
D. Collin
V. Dams
K. Jorens
P. Dubois
J. Gunst
J. Haentjens
De Schryver
N. Dugernier
T. Rezende-Neto
J. Rizoli
S. Santillan
P. Han
Y. Biskup
E. Qu
C. Li
X. Yu
T. Weihua
L. Molano-Franco
D. Rojas
J. Oviedo
J. M. P. Pinilla
D. Cardenas
Y. Celis
E. Arias
M. Vukovic
A. Vudrag
M. Belavic
M. Zunic
J. Kuharic
J. Kricka
I. B. Filipovic-Grcic
I. Tomasevic
B. Obraz
M. Bodulica
B. Dohnal
M. Malaska
J. Kratochvil
M. Satinsky
I. Schwarz
P. Kos
Z. Blahut
L. Maca
J. Protus
M. Kieslichová
E. Nielsen
L. G. Krogh
B. M. Rivadeneira
F. Morales
F. Mora
J. Orozco
A. S. MorochoTutillo
D. R. Vargas
N. R. Yepez
E. S. Villamagua
B. Alsisi
A. Fahmy
A. Dupont
H. Lasocki
S. Paugam-Burtz
C. Foucrier
A. Nica
A. Barjon
G. Mallat
J. Marcotte
G. Leone
M. Duclos
G. Burtin
P. Atchade
E. Mahjoub
Y. Misset
B. Timsit
J. -F.
Dupuis C.
Veber B.
Debarre M.
Collange O.
Pottecher J.
Hecketsweiler S.
Fromentin M.
Tesnière A.
Koch C.
Sander M.
Elke G.
Wrigge H.
Simon P.
Chalkiadaki A.
Tzanidakis C.
Pneumatikos I.
Sertaridou E.
Mastora Z.
Pantazopoulos I.
Papanikolaou M.
Papavasilopoulou T.
Floros J.
Kolonia V.
Diakaki C.
Rallis M.
Paridou A.
Kalogeromitros A.
Romanou V.
Nikolaou C.
Kounougeri K.
Tsigou E.
Psallida V.
Karampela N.
Mandragos K.
Kontoudaki E.
Pentheroudaki A.
Farazi-Chongouki C.
Karakosta A.
Chouris I.
Radu V.
Malliotakis P.
Kokkini S.
Charalambous E.
Kyritsi A.
Koulouras V.
Papathanakos G.
Nagky E.
Lampiri C.
Tsimpoukas F.
Sarakatsanos I.
Georgakopoulos P.
Ravani I.
Prekates A.
Sakellaridis K.
Christopoulos C.
Vrettou E.
Stokkos K.
Pentari A.
Marmanidou K.
Kydona C.
Tsoumaropoulos G.
Bitzani M.
Kontou P.
Voudouris A.
Elli-Nikki Flioni
Antypa E.
Chasou E.
Anisoglou S.
Papageorgiou E.
Paraforou T.
Tsioka A.
Karathanou A.
Vakalos A.
Shah B.
Thakkar C.
Jain N.
Gurjar M.
Baronia A.
Sathe P.
Kulkarni S.
Paul C.
Paul J.
Masjedi M.
Nikandish R.
Zand F.
Sabetian G.
Mahmoodpoor A.
Hashemian S. M.
Bala M.
Flocco R.
Torrente S.
Pota V.
Spadaro S.
Volta C.
Serafini G.
Boraso S.
Tiberio I.
Cortegiani A.
Misseri G.
Barbagallo M.
Nicolotti D.
Forfori F.
Corradi F.
De Pascale
G. Pelagalli
L. Brazzi
L. Vittone
F. G. Russo
A. Simion
D. Cotoia
A. Cinnella
G. Toppin
P. Johnson-Jackson
R. Hayashi
Y. Yamamoto
R. Yasuda
H. Kishihara
Y. Shiotsuka
J. Sanchez-Hurtado
L. A. Tejeda-Huezo
B. Gorordo
L. Ñamendys-Silva
S. A. Garcia-Guillen
F. J. Martinez
M. Romero-Meja
E. Colorado-Dominguez
van den Oever
H. Kalff
K. M. Vermeijden
W. Cornet
A. D. Beck
O. Cimic
N. Dormans
T. Bormans
L. Bakker
Van Duijn
D. Bosman
G. Vos
P. Haas
L. Henein
A. Miranda
A. M. Makikado
L. D. U. Malca
G. E. G. Arroyo-Sanchez
A. Misiewska-Kaczur
A. Akinyi
F. Czuczwar
M. Luczak
K. Sulkowski
W. Tamowicz
B. Swit
B. Baranowski
B. Smuszkiewicz
P. Trojanowska
I. Rzymski
S. Sawinski
M. Trosiak
M. Mikaszewska-Sokolewicz
M. Alves
R. Leal
D. Krystopchuk
A. Mendonca
P. M. H. Pereira
R. A.
de Carvalho
M. R. L. M. Candeias
C. Molinos
E. Ferreira
A. Castro
G. Pereira
J. -M.
Santos L.
Ferreira A.
Pascoalinho D.
Ribeiro R.
Domingos G.
Gomes P.
Nora D.
Costa R. P.
Santos A.
Alsheikhly A. S.
Popescu M.
Grigoras I.
Patrascanu E.
Zabolotskikh I.
Musaeva T.
Gaigolnik D.
Kulabukhov V.
Belskiy V.
Zubareva N.
Tribulev M.
Abdelsalam A.
Aldarsani A.
Al-Khalid M.
Almekhlafi G.
Mandourah Y.
Doklestic K.
Velickovic J.
Velickovic D.
Jankovic R.
Vukovic A.
Skoric-Jokic S.
Radovanovic D.
Richards G.
Alli A.
del Carmen Cordoba Nielfa
M. Iniesta
R. S. Martínez
A. B. -C.
Bernedo C. G.
Gil S. A. P.
Nuvials X.
Garcia J. G.
Peña J. M. G.
Jimenez R.
Herrera L.
Barrachina L. G.
Monzon I. C.
Redondo F. J.
Villazala R.
Zapata D. F. M.
Lopez I. M. V.
Moreno-Gonzalez G.
Lopez-Delgado J. C.
Marin J. S.
Sanchez-Zamora P.
Vidal M. V.
González J. F.
Salinas I.
Hermosa C.
Martinez-Sagasti F.
Domingo-Marín S.
Victorino J. A.
Garcia-Alvarez R.
Calleja
P. L. -A.
de la Torre-Prados
M. -V.
Vidal-Cortes P.
del Río-Carbajo
L. Izura
J. Minguez
V. Alvarez
J. T. Prous
A. P. Paz
D. Roche-Campo
F. Aguilar
G. Belda
J. Rico-Feijoo
J. Aldecoa
C. Zalba-Etayo
B. Lang
M. Dullenkopf
A. Trongtrakul
K. Chtsomkasem
A. Akbas
T. Unal
M. N. Ozcelik
M. Gumus
A. Ramazanoglu
A. Memis
D. Mehmet
I. Urkmez
S. Ozgultekin
A. Demirkiran
O. Aslan
N. A. Kizilaslan
D. Kahveci
F. Ünlü
N. Ozkan
Z. Kaye
C. Jansen
J. O’Neill
O. Nutt
C. Jha
R. Hooker
N. Grecu
I. Petridou
C. Shyamsundar
M. McNamee
L. Trinder
J. Hagan
S. Kelly
C. Silversides
J. Groba
C. B. Boyd
O. Bhowmick
K. Humphreys
S. Summers
C. Polgarova
P. Margarson
M. Dickens
J. Pearson
S. Chinery
E. Hemmings
N. O’Kane
S. Austin
P. Cole
S. Plowright
C. Box
R. Wright
C. Young
L. Montague
L. Parker
R. Morton
B. Ostermann
M. Bilinska
J. Rose
B. O. Reece-Anthony
R. Ryan
C. Hamilton
M. Hopkins
P. Wendon
J. Brescia
G. Ijaz
N. Wood
J. George
M. Toth-Tarsoly
P. Yates
B. Armstrong
M. Scott
C. Boyd
C. Szakmany
T. Rees
D. Pulak
P. Coggon
M. Saha
B. Kent
L. Gibson
B. Camsooksai
J. Reschreiter
H. Morgan
P. Sangaralingham
S. Lowe
A. Vondras
P. Jamadarkhana
S. Cruz
C. Bhandary
R. Hersey
P. Furneval
J. Innes
R. Doble
P. Attwood
B. Parsons
P. Page
V. Zhao
X. Grecu
I. Dalton
J. Hegazy
M. Awad
Y. Naylor
D. Naylor
A. Lee
S. Brevard
S. Davis
University of Queensland [Brisbane]
Department of Intensive Care and Anesthesiology
Università cattolica del Sacro Cuore [Milano] (Unicatt)
University Medical Center [Utrecht]
Johns Hopkins Bloomberg School of Public Health [Baltimore]
Johns Hopkins University (JHU)
Département d'Anesthésie Réanimation
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Centro Hospitalar Universitário São João - Faculty of Medicine - University of Porto - Grupo de Infecção e Sepsis, Porto
Critical Care Department
Joan XXIII University Hospital
Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137))
Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Microbes évolution phylogénie et infections (MEPHI)
Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
Assistance Publique - Hôpitaux de Marseille (APHM)
UCL - SSS/IREC/MEDA - Pôle de médecine aiguë
UCL - (SLuc) Service de soins intensifs
European Soc Intensive Care Med
İÜC, Cerrahpaşa Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
[Blot S, Blot K] Department of Internal Medicine and Pediatrics, Ghent University, Campus UZ Gent, Ghent, Belgium. [Antonelli M] Department of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. Università Cattolica del Sacro Cuore, Rome, Italy. [Arvaniti K] Intensive Care Unit, Papageorgiou University Affiliated Hospital, Thessaloníki, Greece. [Creagh-Brown, B] Surrey Perioperative Anaesthetic Critical Care Collaborative Research Group (SPACeR), Royal Surrey County Hospital, Guildford, UK. Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK. [de Lange D] Department of Intensive Care Medicine, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands. [Rello J] Centro de investigación en red de enfermedades respiratorias (CIBERES), Madrid, Spain. Recerca clínica/Innovació en la pneumònia i sèpsia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
Ünlü, Nurdan
Kahveci, Ferda
CYR-2043-2022
CHB-0826-2022
Assistance Publique-Hôpitaux de Marseille (AP-HM)
Blot S.
Antonelli M.
Arvaniti K.
Blot K.
Creagh-Brown B.
de Lange D.
De Waele J.
Deschepper M.
Dikmen Y.
Dimopoulos G.
Eckmann C.
Francois G.
Girardis M.
Koulenti D.
Labeau S.
Lipman J.
Lipovestky F.
Maseda E.
Montravers P.
Mikstacki A.
Paiva J.-A.
Pereyra C.
Rello J.
Timsit J.-F.
Vogelaers D.
Lamrous A.
Rezende-Neto J.
Cardenas Y.
Vymazal T.
Fjeldsoee-Nielsen H.
Kott M.
Kostoula A.
Javeri Y.
Einav S.
Makikado L.D.U.
Tomescu D.
Gritsan A.
Jovanovic B.
Venkatesan K.
Mirkovic T.
Emmerich M.
Canale M.
Dietz L.S.
Ilutovich S.
Minope J.T.S.
Silva R.B.
Montenegro M.A.
Martin P.
Saul P.
Chediack V.
Sutton G.
Couce R.
Balasini C.
Gonzalez S.
Lascar F.M.
Descotte E.J.
Gumiela N.S.
Pino C.A.
Cesio C.
Valgolio E.
Cunto E.
Dominguez C.
Nelson N.F.
Abegao E.M.
Pozo N.C.
Bianchi L.
Correger E.
Pastorino M.L.
Miyazaki E.A.
Grubissich N.
Garcia M.
Bonetto N.
Quevedo N.E.
Gomez C.D.
Queti F.
Estevarena L.G.
Fernandez R.
Santolaya I.
Grangeat S.H.
Doglia J.
Zakalik G.
Pellegrini C.
Lloria M.M.
Chacon M.E.
Fumale M.
Leguizamon M.
Hidalgo I.B.
Tiranti R.J.
Capponi P.
Tita A.
Cardonnet L.
Bettini L.
Ramos A.
Lovesio L.
Miranda E.M.
Farfan A.B.
Tolosa C.
Segura L.
Bellocchio A.
Alvarez B.
Manzur A.
Lujan R.
Fernandez N.
Scarone N.
Zazu A.
Groh C.
Fletcher J.
Smith J.
Azad R.
Chavan N.
Wong H.
Kol M.
Campbell L.
Starr T.
Roberts B.
Wibrow B.
Warhurst T.
Chinthamuneedi M.
Ferney B.B.
Simon M.
De Backer D.
Wittebole X.
De Bels D.
Collin V.
Dams K.
Jorens P.
Dubois J.
Gunst J.
Haentjens L.
De Schryver N.
Dugernier T.
Rizoli S.
Santillan P.
Han Y.
Biskup E.
Qu C.
Li X.
Yu T.
Weihua L.
Molano-Franco D.
Rojas J.
Oviedo J.M.P.
Pinilla D.
Celis E.
Arias M.
Vukovic A.
Vudrag M.
Belavic M.
Zunic J.
Kuharic J.
Kricka I.B.
Filipovic-Grcic I.
Tomasevic B.
Obraz M.
Bodulica B.
Dohnal M.
Malaska J.
Kratochvil M.
Satinsky I.
Schwarz P.
Kos Z.
Blahut L.
Maca J.
Protus M.
Kieslichova E.
Nielsen L.G.
Krogh B.M.
Rivadeneira F.
Morales F.
Mora J.
Orozco A.S.
MorochoTutillo D.R.
Vargas N.R.
Yepez E.S.
Villamagua B.
Alsisi A.
Fahmy A.
Dupont H.
Lasocki S.
Paugam-Burtz C.
Foucrier A.
Nica A.
Barjon G.
Mallat J.
Marcotte G.
Leone M.
Duclos G.
Burtin P.
Atchade E.
Mahjoub Y.
Misset B.
Dupuis C.
Veber B.
Debarre M.
Collange O.
Pottecher J.
Hecketsweiler S.
Fromentin M.
Tesniere A.
Koch C.
Sander M.
Elke G.
Wrigge H.
Simon P.
Chalkiadaki A.
Tzanidakis C.
Pneumatikos I.
Sertaridou E.
Mastora Z.
Pantazopoulos I.
Papanikolaou M.
Papavasilopoulou T.
Floros J.
Kolonia V.
Diakaki C.
Rallis M.
Paridou A.
Kalogeromitros A.
Romanou V.
Nikolaou C.
Kounougeri K.
Tsigou E.
Psallida V.
Karampela N.
Mandragos K.
Kontoudaki E.
Pentheroudaki A.
Farazi-Chongouki C.
Karakosta A.
Chouris I.
Radu V.
Malliotakis P.
Kokkini S.
Charalambous E.
Kyritsi A.
Koulouras V.
Papathanakos G.
Nagky E.
Lampiri C.
Tsimpoukas F.
Sarakatsanos I.
Georgakopoulos P.
Ravani I.
Prekates A.
Sakellaridis K.
Christopoulos C.
Vrettou E.
Stokkos K.
Pentari A.
Marmanidou K.
Kydona C.
Tsoumaropoulos G.
Bitzani M.
Kontou P.
Voudouris A.
Elli-Nikki
Flioni
Antypa E.
Chasou E.
Anisoglou S.
Papageorgiou E.
Paraforou T.
Tsioka A.
Karathanou A.
Vakalos A.
Shah B.
Thakkar C.
Jain N.
Gurjar M.
Baronia A.
Sathe P.
Kulkarni S.
Paul C.
Paul J.
Masjedi M.
Nikandish R.
Zand F.
Sabetian G.
Mahmoodpoor A.
Hashemian S.M.
Bala M.
Flocco R.
Torrente S.
Pota V.
Spadaro S.
Volta C.
Serafini G.
Boraso S.
Tiberio I.
Cortegiani A.
Misseri G.
Barbagallo M.
Nicolotti D.
Forfori F.
Corradi F.
De Pascale G.
Pelagalli L.
Brazzi L.
Vittone F.G.
Russo A.
Simion D.
Cotoia A.
Cinnella G.
Toppin P.
Johnson-Jackson R.
Hayashi Y.
Yamamoto R.
Yasuda H.
Kishihara Y.
Shiotsuka J.
Sanchez-Hurtado L.A.
Tejeda-Huezo B.
Gorordo L.
Namendys-Silva S.A.
Garcia-Guillen F.J.
Martinez M.
Romero-Meja E.
Colorado-Dominguez E.
van den Oever H.
Kalff K.M.
Vermeijden W.
Cornet A.D.
Beck O.
Cimic N.
Dormans T.
Bormans L.
Bakker J.
Van Duijn D.
Bosman G.
Vos P.
Haas L.
Henein A.
Miranda A.M.
Malca G.E.G.
Arroyo-Sanchez A.
Misiewska-Kaczur A.
Akinyi F.
Czuczwar M.
Luczak K.
Sulkowski W.
Tamowicz B.
Swit B.
Baranowski B.
Smuszkiewicz P.
Trojanowska I.
Rzymski S.
Sawinski M.
Trosiak M.
Mikaszewska-Sokolewicz M.
Alves R.
Leal D.
Krystopchuk A.
Mendonca P.M.H.
Pereira R.A.
de Carvalho M.R.L.M.
Candeias C.
Molinos E.
Ferreira A.
Castro G.
Pereira J.-M.
Santos L.
Pascoalinho D.
Ribeiro R.
Domingos G.
Gomes P.
Nora D.
Costa R.P.
Santos A.
Alsheikhly A.S.
Popescu M.
Grigoras I.
Patrascanu E.
Zabolotskikh I.
Musaeva T.
Gaigolnik D.
Kulabukhov V.
Belskiy V.
Zubareva N.
Tribulev M.
Abdelsalam A.
Aldarsani A.
Al-Khalid M.
Almekhlafi G.
Mandourah Y.
Doklestic K.
Velickovic J.
Velickovic D.
Jankovic R.
Skoric-Jokic S.
Radovanovic D.
Richards G.
Alli A.
del Carmen Cordoba Nielfa M.
Iniesta R.S.
Martinez A.B.-C.
Bernedo C.G.
Gil S.A.P.
Nuvials X.
Garcia J.G.
Pena J.M.G.
Jimenez R.
Herrera L.
Barrachina L.G.
Monzon I.C.
Redondo F.J.
Villazala R.
Zapata D.F.M.
Lopez I.M.V.
Moreno-Gonzalez G.
Lopez-Delgado J.C.
Marin J.S.
Sanchez-Zamora P.
Vidal M.V.
Gonzalez J.F.
Salinas I.
Hermosa C.
Martinez-Sagasti F.
Domingo-Marin S.
Victorino J.A.
Garcia-Alvarez R.
Calleja P.L.-A.
de la Torre-Prados M.-V.
Vidal-Cortes P.
del Rio-Carbajo L.
Izura J.
Minguez V.
Alvarez J.T.
Prous A.P.
Paz D.
Roche-Campo F.
Aguilar G.
Belda J.
Rico-Feijoo J.
Aldecoa C.
Zalba-Etayo B.
Lang M.
Dullenkopf A.
Trongtrakul K.
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Akbas T.
Unal M.N.
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Gumus A.
Ramazanoglu A.
Memis D.
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Summers C.
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Dickens J.
Pearson S.
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Lee S.
Brevard S.
Davis N.
Blot, Stijn [0000-0003-2145-0345]
Apollo - University of Cambridge Repository
Gunst, Jan
Epidemiology
Intensive Care
Blot
S., aEmail Author
Antonelli, M. b.
C, Arvaniti
Blot, K. d.
Creagh-Brown, K. a.
B. e., F
De, Lange
D., G.
De, Waele
Deschepper, J. h.
Dikmen, M. i.
Dimopoulos, Y. j.
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Girardis, G. m.
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D. o., P
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W, Mikstacki
A. x., Y
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Kott, M.
Kostoula, A.
Javeri, Y.
Einav, S.
Makikado, L. D. U.
Tomescu, D.
Gritsan, A.
Jovanovic, B.
Venkatesan, K.
Mirkovic, T.
Creagh-Brown, B.
Emmerich, M.
Canale, M.
Dietz, L. S.
Ilutovich, S.
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Silva, R. B.
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Source :
Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine & Silversides, J 2019, ' Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project ', Intensive Care Medicine, vol. 45, no. 12, pp. 1703-1717 . https://doi.org/10.1007/s00134-019-05819-3, Intensive Care Medicine, r-FISABIO: Repositorio Institucional de Producción Científica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Intensive Care Medicine, 2019, 45 (12), pp.1703-1717. ⟨10.1007/s00134-019-05819-3⟩, Intensive care medicine, Vol. 45, no.12, p. 1703-1717 (2019), Intensive Care Medicine, 45(12), 1703. Springer Verlag, Intensive care medicine, INTENSIVE CARE MEDICINE, Scientia, Intensive Care Medicine, Springer Verlag, 2019, 45 (12), pp.1703-1717. ⟨10.1007/s00134-019-05819-3⟩, r-FISABIO. Repositorio Institucional de Producción Científica, instname, Intensive Care Medicine, 45(12), 1703-1717. Springer-Verlag, Volume 45, Issue 12, Blot, S, Antonelli, M, Arvaniti, K, Blot, K, Creagh-Brown, B, de Lange, D, De Waele, J, Deschepper, M, Dikmen, Y, Dimopoulos, G, Eckmann, C, Francois, G, Girardis, M, Koulenti, D, Labeau, S, Lipman, J, Lipovestky, F, Maseda, E, Montravers, P, Mikstacki, A, Paiva, J A, Pereyra, C, Rello, J, Timsit, J F, Vogelaers, D & the Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine 2019, ' Epidemiology of intra-abdominal infection and sepsis in critically ill patients : “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project ', Intensive Care Medicine, vol. 45, no. 12, pp. 1703-1717 . https://doi.org/10.1007/s00134-019-05819-3
Publication Year :
2019

Abstract

Pardo-Oviedo, Juan Mauricio/0000-0003-0084-3449; Lopez-Delgado, Juan Carlos/0000-0003-3324-1129; Corradi, Francesco/0000-0002-5588-2608; De Backer, Daniel/0000-0001-9841-5762; POTA, VINCENZO/0000-0001-9999-3388; Tomescu, Dana/0000-0001-9673-5754; Sabetian, Golnar/0000-0001-8764-2150; Girardis, Massimo/0000-0002-2453-0829; Brazzi, Luca/0000-0001-7059-0622; Leone, Marc/0000-0002-3097-758X; Zabolotskikh, Igor Borisovich/0000-0002-3623-2546; De Lange, Dylan/0000-0002-0191-7270; ALMEKHLAFI, GHALEB A./0000-0002-0323-7025; Elke, Gunnar/0000-0002-4948-1605; Grigoras, Ioana/0000-0001-9412-9574; Czuczwar, Miroslaw/0000-0002-9025-6717; Nora, David/0000-0002-1133-7368; Masjedi, Mansoor/0000-0001-6175-9289; Gunst, Jan/0000-0003-2470-6393; Vidal-Cortes, Pablo/0000-0003-0225-9975; Szakmany, Tamas/0000-0003-3632-8844; Dimopoulos, George/0000-0002-3784-3103; Rello, Jordi/0000-0003-0676-6210; U nal, Necmettin/0000-0002-9440-7893; Tiberio, Iolanda FLC/0000-0002-5662-7895; Cortegiani, Andrea/0000-0003-1416-9993; Morton, Ben/0000-0002-6164-2854; Labeau, Sonia/0000-0003-3863-612X; Velickovic, Dejan/0000-0002-7312-2880; Paul, John/0000-0002-9307-3465; Pereira, Rui/0000-0002-3010-8384; Silversides, Jon/0000-0002-9562-5462; Paiva, Jose-Artur/0000-0003-4323-0220; Smuszkiewicz, Piotr/0000-0003-3067-8229; Paul, Cherish/0000-0001-6133-0036; Santos, Lurdes/0000-0002-0622-6823; PANTAZOPOULOS, IOANNIS/0000-0002-8846-519X; Ostermann, Marlies/0000-0001-9500-9080; Blot, Stijn/0000-0003-2145-0345; Naylor, Amanda/0000-0002-6431-0230; Shyamsundar, Murali/0000-0003-3797-8080; Aldecoa, Cesar/0000-0001-8789-5959; Summers, Charlotte/0000-0002-7269-2873; biskup, ewelina/0000-0002-9871-927X; Cornet, Alexander/0000-0002-9917-5251; Trenado Alvarez, Jose/0000-0002-2930-0766; Volta, Carlo/0000-0003-3533-6121; Gritsan, Alexey/0000-0002-0500-2887; Urkmez, Seval/0000-0002-3412-4226 WOS:000493268200001 PubMed ID: 31664501 PurposeTo describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression (infection, sepsis, and septic shock).MethodsWe performed a multicenter (n=309), observational, epidemiological study including adult ICU patients diagnosed with intra-abdominal infection. Risk factors for mortality were assessed by logistic regression analysis.ResultsThe cohort included 2621 patients. Setting of infection acquisition was community-acquired in 31.6%, early onset hospital-acquired in 25%, and late-onset hospital-acquired in 43.4% of patients. Overall prevalence of antimicrobial resistance was 26.3% and difficult-to-treat resistant Gram-negative bacteria 4.3%, with great variation according to geographic region. No difference in prevalence of antimicrobial resistance was observed according to setting of infection acquisition. Overall mortality was 29.1%. Independent risk factors for mortality included late-onset hospital-acquired infection, diffuse peritonitis, sepsis, septic shock, older age, malnutrition, liver failure, congestive heart failure, antimicrobial resistance (either methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Gram-negative bacteria, or carbapenem-resistant Gram-negative bacteria) and source control failure evidenced by either the need for surgical revision or persistent inflammation.ConclusionThis multinational, heterogeneous cohort of ICU patients with intra-abdominal infection revealed that setting of infection acquisition, anatomical disruption, and severity of disease expression are disease-specific phenotypic characteristics associated with outcome, irrespective of the type of infection. Antimicrobial resistance is equally common in community-acquired as in hospital-acquired infection. Pfizer investigator-initiated research grant AbSeS is a Trials Group Study of the European Society of Intensive Care Medicine. The study was supported by a Pfizer investigator-initiated research grant.

Subjects

Subjects :
Infection risk
Male
BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences
Antibiotic resistance
Tracte gastrointestinal - Malalties
Definitions
Critical Care and Intensive Care Medicine
THERAPY
DEFINITIONS
Infections::Intraabdominal Infections [DISEASES]
0302 clinical medicine
Intensive care
Intra-abdominal infection
Mortality
Multidrug resistance
Peritonitis
Sepsis
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Observational study
Septic shock
ComputingMilieux_MISCELLANEOUS
Critical Illness/epidemiology
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti
Intraabdominal Infections/epidemiology
Abdominal infection
Multicenter study
3. Good health
Management
Clinical trial
Cohort
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
Cohort analysis
Community acquired infection
Cohort study
Human
medicine.medical_specialty
Carbapenem resistance
Critical Illness
Peritoneal dialysis
Vancomycin resistant enterococcus
Major clinical study
Article
03 medical and health sciences
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Settore MED/41 - ANESTESIOLOGIA
Humans
Critical care medicine
Hospital infection
Aged
Science & Technology
Liver failure
Antibiotic therapy
medicine.disease
[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Epidemiologic Studies
030228 respiratory system
Intensive Care Unit
Sepsis (Diptera)
Septic Shock
Risk factor
Human medicine
General & internal medicine
Congestive heart failure
Original
Cohort Studies
Risk Factors
Cause of Death
Epidemiology
Prevalence
Medicine and Health Sciences
Abdominal abscess
Sepsis/epidemiology
Middle aged
Antifungal therapy
2. Zero hunger
Peritoniti
Antibiotic agent
Biliary tract infection
Middle Aged
infecciones bacterianas y micosis::infección::infecciones intraabdominales [ENFERMEDADES]
PREVALENCE
Infections::Sepsis [DISEASES]
técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::estudios de cohortes [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS]
Methicillin resistant staphylococcus aureus
Raonament basat en casos
Female
Critically ill patient
Life Sciences & Biomedicine
Antifungal agent
Adult
Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT]
Predictive value
infecciones bacterianas y micosis::infección::sepsis [ENFERMEDADES]
NO
Critical Care Medicine
Internal medicine
General & Internal Medicine
medicine
MANAGEMENT
Journal Article
[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology
Septicèmia
business.industry
Pancreas disease
Malnutrition
030208 emergency & critical care medicine
Typhlitis
Toxic megacolon
Intraabdominal Infections
Therapy
Late onset disorder
business

Details

Language :
English
ISSN :
14321238 and 03424642
Database :
OpenAIRE
Journal :
Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine & Silversides, J 2019, ' Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project ', Intensive Care Medicine, vol. 45, no. 12, pp. 1703-1717 . https://doi.org/10.1007/s00134-019-05819-3, Intensive Care Medicine, r-FISABIO: Repositorio Institucional de Producción Científica, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Intensive Care Medicine, 2019, 45 (12), pp.1703-1717. ⟨10.1007/s00134-019-05819-3⟩, Intensive care medicine, Vol. 45, no.12, p. 1703-1717 (2019), Intensive Care Medicine, 45(12), 1703. Springer Verlag, Intensive care medicine, INTENSIVE CARE MEDICINE, Scientia, Intensive Care Medicine, Springer Verlag, 2019, 45 (12), pp.1703-1717. ⟨10.1007/s00134-019-05819-3⟩, r-FISABIO. Repositorio Institucional de Producción Científica, instname, Intensive Care Medicine, 45(12), 1703-1717. Springer-Verlag, Volume 45, Issue 12, Blot, S, Antonelli, M, Arvaniti, K, Blot, K, Creagh-Brown, B, de Lange, D, De Waele, J, Deschepper, M, Dikmen, Y, Dimopoulos, G, Eckmann, C, Francois, G, Girardis, M, Koulenti, D, Labeau, S, Lipman, J, Lipovestky, F, Maseda, E, Montravers, P, Mikstacki, A, Paiva, J A, Pereyra, C, Rello, J, Timsit, J F, Vogelaers, D & the Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine 2019, ' Epidemiology of intra-abdominal infection and sepsis in critically ill patients : “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project ', Intensive Care Medicine, vol. 45, no. 12, pp. 1703-1717 . https://doi.org/10.1007/s00134-019-05819-3
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edsair.doi.dedup.....0f3c7cb4866330431d1d3c5be59593e2
Full Text :
https://doi.org/10.1007/s00134-019-05819-3
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