Back to Search
Start Over
MRI of the pharynx in ischemic stroke patients with and without obstructive sleep apnea
- Publication Year :
- 2010
-
Abstract
- Obstructive sleep apnea (OSA) is common after stroke and associated with poor stroke outcomes. Whether OSA after acute stroke is caused by anatomic, physiologic, or both etiologies has not been studied. We therefore used brain magnetic resonance imaging (MRI) scans to assess oropharyngeal anatomy in stroke patients with and without OSA.Patients within 7 days of ischemic stroke underwent nocturnal polysomnography. Sagittal T1-weighted MRI performed for clinical purposes was used to measure retropalatal distance, soft palatal length, soft palatal thickness, retroglossal space, and tongue length. Nasopharyngeal area and high retropharyngeal area were measured from axial T2-weighted images, and lateral pharyngeal wall thickness from coronal T1-weighted images.Among 27 subjects, 18 (67%) had OSA (apnea/hypopnea index (AHI)5). Demographics, vascular risk factors, and stroke severity were similar in the two groups. Median retropalatal distance was shorter in subjects with OSA (Wilcoxon rank-sum test, p=0.03). Shorter retropalatal distance was associated with higher AHI (linear regression, p=0.04). None of the other morphological characteristics differed.Anatomic difference between awake acute stroke patients with and without OSA shows that the sleep disorder cannot be attributed solely to sleep, sleeping position, or changes in neuromuscular control that are specific to the sleep state.
- Subjects :
- Male
medicine.medical_specialty
Polysomnography
Article
stomatognathic system
Neuroimaging
Reference Values
Internal medicine
Nasopharynx
Image Processing, Computer-Assisted
Medicine
Humans
cardiovascular diseases
Wakefulness
Stroke
Aged
Sleep Apnea, Obstructive
medicine.diagnostic_test
business.industry
Cerebral infarction
Airway Resistance
Sleep apnea
Magnetic resonance imaging
General Medicine
Cerebral Infarction
Organ Size
Middle Aged
medicine.disease
Magnetic Resonance Imaging
nervous system diseases
respiratory tract diseases
Obstructive sleep apnea
Oxygen
ROC Curve
Anesthesia
Etiology
Cardiology
Pharynx
Female
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....0f5578d889a35b2853297db3c5701a3d