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Supplementary Tables S1-S4 and Figures S1-S3 from Antitumor Activity in RAS-Driven Tumors by Blocking AKT and MEK
- Publication Year :
- 2023
- Publisher :
- American Association for Cancer Research (AACR), 2023.
-
Abstract
- Supplementary Tables S1-S4 and Figures S1-S3. Tables S1/S2: % tumor response in mice with HCT116 and A2058 tumor xenografts following treatment; Table S3: Diagram showing dose-decision guidelines utilized in the MK-2206 clinical study based on observed toxicities; Table S4: number of patients with drug-related AEs in all courses of treatment; Figure S1/S2: Line graph showing the relative tumor volume and body weight observed in patients over time expressed in terms of days following treatment; Figure S3: Patient presenting with Grade III rash
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....0f597346417fd8a518a7f25a4fa93a7d