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Supplementary Figures 1 - 3, Table 1 from Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia

Authors :
Vahid Asnafi
Jacques Ghysdael
Elizabeth Macintyre
Olivier Hermine
David-Alexandre Gross
Lucienne Chatenoud
Salvatore Spicuglia
Hervé Dombret
Norbert Ifrah
Françoise Pflumio
Els Verhoeyen
François-Loïc Cosset
Michael Dussiot
Melania Tesio
Ludovic Lhermitte
Cindy Da Costa de Jesus
Mohamed Belhocine
Benedetta Zaniboni
Francesca Rocchetti
Christine Tran Quang
Nuno R. dos Santos
Amélie Trinquand
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Figure 1. Anti-CD3 stimulation of primary human T-ALLs. Supplementary Figure 2. TCR stimulation by in vivo administration of agonistic monoclonal antibody in a preventive setting inhibits human TCR+ T-ALL development. Supplementary Figure 3. TCR signaling is essential to the anti-leukemic effect of OKT3. Supplementary Table 1. Immunophenotypic and oncogenic characteristics of T-ALL samples.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....0fc88f82dad967c7efadb3786c3315ac