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SupplementalTables from Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition

Authors :
Uri Tabori
Cynthia E. Hawkins
Pamela S. Ohashi
Trevor J. Pugh
Adam Shlien
Michael D. Taylor
John M. Maris
David Malkin
Carol Durno
Melyssa Aronson
Daniel A. Morgenstern
Eric Bouffet
Gary Mason
David Samuel
Sangeetha N. Kalimuthu
Lazar Joksimovic
Michal Zapotocky
Matthew Zatzman
A. Sorana Morrissy
Liana Nobre
Nuno M. Nunes
Martin Komosa
Robert Siddaway
Sumedha Sudhaman
Melissa Edwards
Alexandra N. Riemenschneider
Simone C. Stone
Melissa A. Galati
Brittany B. Campbell
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Table S1: Summary of likely pathogenic mutations detected in Foundation Medicine cohort of 1215 pediatric cancers. Table S2: Summary of RAS/MAPK pathway mutations and consequences detected in 48 RRD cancers.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....1031a84e4fc1653137656aec9d2eb951
Full Text :
https://doi.org/10.1158/2159-8290.22540376