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ChemInform Abstract: Alkylation and Aldol Reactions of Acyl Derivatives of N-1-(1′-Naphthyl)ethyl-O-tert-butylhydroxylamine: Asymmetric Synthesis of α-Alkoxy-, α-Substituted-β-alkoxy- and α,β-Dialkoxyaldehydes

Authors :
Christopher J. Goodwin
Edward D. Savory
Paul M. Roberts
Andrew Smith
Ai M. Flechter
David Hepworth
Stephen G. Davies
Alexander N. Chernega
R. Shyam Prasad
James E. Thomson
Source :
ChemInform. 41
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

Alternatively, the chiral auxiliary promotes aldol reactions to give syn-aldol products such as (XIII), (XVI), or (XX) with good diastereocontrol over both newly generated stereogenic centers.

Details

ISSN :
09317597
Volume :
41
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi.dedup.....10565ddb9b2a97014bf9e42f6a1cdbb9
Full Text :
https://doi.org/10.1002/chin.201039053