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Infant progressive colonic stenosis caused by antibiotic-related Clostridium difficile colitis – a case report and literature review
- Source :
- BMC Pediatrics, BMC Pediatrics, Vol 18, Iss 1, Pp 1-5 (2018)
- Publication Year :
- 2018
- Publisher :
- BioMed Central, 2018.
-
Abstract
- Background Colonic stenosis is a rare cause of pediatric intestinal obstruction. The root cause underlying colonic stenosis is unclear and there is no fixed operation. Case presentation We reported on a male infant with progressive colonic stenosis caused by antibiotic-related colitis. The infant was admitted to our hospital with pneumonia but developed progressive abdominal distension and diarrhea following antibiotic treatment with meropenem. Initial testing of stool culture showed a Clostridium difficile infection. Additional testing with barium enema imaging showed stenosis at the junction of the sigmoid and descending colon at first and another stenosis occurred at the right half of the transverse colon 3 weeks later. Staged surgical treatment was performed with primary resections of the two parts suffering stenosis, ileostomy, and secondary intestinal anastomosis. A pathological exam then confirmed the diagnosis of colonic stenosis and the patient had an uneventful recovery and has been recovering well as evidenced by the 1-year follow-up. Conclusions Based on a review of the literature and our case report, we found that progressive colonic stenosis caused by colitis due to antibiotic-related Clostridium difficile infection is rare in infants. Infants with colitis and repeated abdominal distention, vomiting, and constipation should be treated with the utmost caution and screened. Despite this, clinical manifestations depended on the severity of the stenosis. Barium enema, colonoscopy, laprascopy or laparotomy and colonic biopsy are helpful for diagnosis and differential diagnosis. While both one-stage and multiple-stage operations are feasible, a staged operation should be used for multiple colonic stenoses.
- Subjects :
- Male
medicine.medical_specialty
medicine.medical_treatment
Case Report
Constriction, Pathologic
030230 surgery
Gastroenterology
Clostridium Difficile Colitis
03 medical and health sciences
Colonic Diseases
0302 clinical medicine
030225 pediatrics
Internal medicine
Laparotomy
medicine
Humans
Colitis
Barium enema
Colonitis
business.industry
lcsh:RJ1-570
Transverse colon
Infant, Newborn
lcsh:Pediatrics
Clostridium difficile
Meropenem
Abdominal distension
medicine.disease
digestive system diseases
Anti-Bacterial Agents
Radiography
Stenosis
Pediatrics, Perinatology and Child Health
Clostridium Infections
medicine.symptom
Colonic stenosis
business
Intestinal Obstruction
Subjects
Details
- Language :
- English
- ISSN :
- 14712431
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- BMC Pediatrics
- Accession number :
- edsair.doi.dedup.....1068a748052f4c909426ac8437fde443