Back to Search
Start Over
Revascularization with and without Platelet-rich Plasma in Nonvital, Immature, Anterior Teeth: A Pilot Clinical Study
- Source :
- Journal of Endodontics. 38:1581-1587
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- Introduction This study was conducted to evaluate and compare maturogenesis induced by revascularization with and without platelet-rich plasma (PRP). Methods Twenty patients with nonvital, immature anterior teeth were randomly categorized into 2 groups. Subsequent to chemomechanical preparation, revascularization with and without PRP carried on a collagen sponge was induced in groups 1 and 2, respectively. The cases were followed up clinically and radiographically at 6- and 12-month intervals. Results Clinically, all cases were asymptomatic with complete resolution of signs and symptoms. Radiographically, there was a marked difference in periapical healing, apical closure, and dentinal wall thickening in group 2 in comparison with group 1. However, root lengthening was comparable for both of the procedures. Conclusions Revascularization is a conservative and an effective method for inducing maturogenesis in nonvital, immature teeth. Supplementations with PRP can potentially improve the desired biological outcome of this regenerative technique.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
medicine.medical_treatment
Radiography
Neovascularization, Physiologic
Dentistry
Pilot Projects
Signs and symptoms
Revascularization
Asymptomatic
Clinical study
Young Adult
Tooth Apex
medicine
Humans
Regeneration
Radiography, Bitewing
General Dentistry
Anterior teeth
Tooth, Nonvital
Wound Healing
Tissue Scaffolds
Apexification
Platelet-Rich Plasma
business.industry
Periapical Diseases
Surgery
Incisor
Collagen sponge
Platelet-rich plasma
Dentin
Odontogenesis
Female
medicine.symptom
business
Root Canal Preparation
Follow-Up Studies
Subjects
Details
- ISSN :
- 00992399
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Journal of Endodontics
- Accession number :
- edsair.doi.dedup.....10f2e49682b121e2dc63a0f80ca5b9ee