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Physician's global assessment is often useful in SLE, but not always: the case of clinical remission
- Source :
- Annals of the rheumatic diseases. 81(5)
- Publication Year :
- 2020
-
Abstract
- We read with interest the paper by Aranow et al 1 where physician’s global assessment (PGA) displayed excellent inter-rater reliability, which could rely on the inclusion of highly selected lupus experts, as stated by the authors themselves. Indeed, in previous studies, PGA showed a high intra-rater and inter-rater variability,2 3 consistently with PGA being a subjective measure. The high inter-rater reliability observed by the authors is surprising considering that the timeframe for assessing disease activity significantly varied among respondents: 36.7% scored PGA over the previous 7–10 days, 36.7% over the previous month, the remainder over shorter or longer periods of time. Additionally, in almost one-third of respondents, lupus damage was considered when scoring PGA. Notably, the authors suggest that PGA should be scored after considering laboratory results, owing to a better correlation with systemic lupus erythematosus (SLE) disease activity index-2000 (SLEDAI-2K) of postlaboratory versus prelaboratory PGA. …
- Subjects :
- 030203 arthritis & rheumatology
0301 basic medicine
medicine.medical_specialty
Systemic lupus erythematosus
business.industry
Immunology
Remission Induction
Laboratory results
medicine.disease
Severity of Illness Index
General Biochemistry, Genetics and Molecular Biology
Disease activity
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Rheumatology
Internal medicine
Physicians
Epidemiology
Immunology and Allergy
Medicine
Humans
Lupus Erythematosus, Systemic
business
Subjects
Details
- ISSN :
- 14682060
- Volume :
- 81
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Annals of the rheumatic diseases
- Accession number :
- edsair.doi.dedup.....11126369c71de71f85f2a6b9b71c3772