Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma

Authors :: Kiran Ghodke
Nikhil Rabade
Sumeet Gujral
Pratibha Amare
Nikhil Patkar
Asma Bibi
Prashant Tembhare
P.G. Subramanian
Source :: Indian Journal of Pathology and Microbiology, Vol 59, Iss 3, Pp 410-412 (2016)
Publication Year :: 2016
Publisher :: Medknow, 2016.
Abstract: Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.

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