Accumulation of anE,E,E-Triene by the Monensin-Producing Polyketide Synthase when Oxidative Cyclization is Blocked

Authors :: Peter F. Leadlay
Yuliya Demydchuk
Andrew R. Gallimore
Christian B. W. Stark
Barbara M. Harvey
Apoorva Bhatt
James Staunton
Jonathan B. Spencer
Source :: Angewandte Chemie International Edition. 44:7075-7078
Publication Year :: 2005
Publisher :: Wiley, 2005.

Subjects :: Oxidative cyclization
biology
Monensin
Molecular Conformation
Stereoisomerism
Polyenes
General Chemistry
Protein engineering
Streptomyces
Catalysis
chemistry.chemical_compound
Biosynthesis
chemistry
Biochemistry
Cyclization
Polyketide synthase
biology.protein
Oxidation-Reduction
Polyketide Synthases

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