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Specific lymphocyte sensitization in cancer: is there a common antigen in human malignant neoplasia?
- Source :
- British medical journal. 2(5762)
- Publication Year :
- 1971
-
Abstract
- From human cancer tissue a basic protein can be extracted by the method which yields encephalitogenic factor when applied to human brain. This tumour basic protein (obtained from several different neoplasms) acts as an antigen in the cytopherometric test for malignant neoplasia and in general gives higher results than does brain basic protein. The reverse is true when degenerative disease of the nervous system is studied. The basic protein extractable from brain and from tumours thus has some degree of specificity probably referable to its amino-acid sequence.
- Subjects :
- Nervous system
Adult
Male
Pathology
medicine.medical_specialty
Adolescent
Lymphocyte
Nerve Tissue Proteins
Biology
Epitope
Epitopes
Degenerative disease
Antigen
Antigens, Neoplasm
Neoplasms
medicine
Hypersensitivity
Humans
Amino Acid Sequence
Lymphocytes
Antigens
Sensitization
General Environmental Science
Aged
Macrophages
General Engineering
Cancer
General Medicine
Human brain
Papers and Originals
Middle Aged
medicine.disease
Neoplasm Proteins
medicine.anatomical_structure
Child, Preschool
Cell Migration Inhibition
General Earth and Planetary Sciences
Female
Nervous System Diseases
Subjects
Details
- ISSN :
- 00071447
- Volume :
- 2
- Issue :
- 5762
- Database :
- OpenAIRE
- Journal :
- British medical journal
- Accession number :
- edsair.doi.dedup.....11d74f5c65316d893491ad80f7be519a