Back to Search Start Over

Sunburn, sun exposure, and sun sensitivity in the Study of Nevi in Children

Authors :
Susan A. Oliveria
Stephen W. Dusza
Ashfaq A. Marghoob
Allan C. Halpern
Arshi Arora
Jaya M. Satagopan
Alan C. Geller
Martin A. Weinstock
Irene Orlow
Michael A. Marchetti
Alon Scope
Source :
Annals of Epidemiology. 25:839-843.e4
Publication Year :
2015
Publisher :
Elsevier BV, 2015.

Abstract

To examine the joint effect of sun exposure and sunburn on nevus counts (on the natural logarithm scale; log nevi) and the role of sun sensitivity.We describe an analysis of cross-sectional data from 443 children enrolled in the prospective Study of Nevi in Children. To evaluate the joint effect, we partitioned the sum of squares because of interaction between sunburn and sun exposure into orthogonal components representing (1) monotonic increase in log nevi with increasing sun exposure (rate of increase of log nevi depends on sunburn), and (2) nonmonotonic pattern.In unadjusted analyses, there was a marginally significant monotonic pattern of interaction (P = .08). In adjusted analyses, sun exposure was associated with higher log nevi among those without sunburn (P .001), but not among those with sunburn (P = .14). Sunburn was independently associated with log nevi (P = .02), even though sun sensitivity explained 29% (95% confidence interval: 2%-56%, P = .04) of its effect. Children with high sun sensitivity and sunburn had more nevi, regardless of sun exposure.A program of increasing sun protection in early childhood as a strategy for reducing nevi, when applied to the general population, may not equally benefit everyone.

Details

ISSN :
10472797
Volume :
25
Database :
OpenAIRE
Journal :
Annals of Epidemiology
Accession number :
edsair.doi.dedup.....11dfc43cf367c043e1d3d38a10a5f7a7
Full Text :
https://doi.org/10.1016/j.annepidem.2015.05.004