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Intraarterial thrombolysis and stent placement for acute basilar artery occlusion
- Source :
- Journal of vascular and interventional radiology : JVIR. 21(9)
- Publication Year :
- 2009
-
Abstract
- Purpose To study retrospectively the prognostic factors for acute basilar artery occlusion treated with intraarterial thrombolysis and stent placement. Materials and Methods Within 3–48 hours of disease onset, 52 patients with basilar artery occlusion were treated with emergency intraarterial thrombolysis with recombinant tissue plasminogen activator (rtPA) or urokinase (UK) or intraarterial thrombolysis combined with stent placement. Sixteen patients simultaneously received stent placement for the partial recanalization of basilar artery occlusion after intraarterial thrombolysis. The National Institutes of Health Stroke Scale (NIHSS) scores and the modified Rankin Scale (mRS) scores of the patients were estimated. Results A favorable clinical outcome occurred in 22 patients (42.3%), and 20 patients (38.5%) died. The survival rate was 61.5% (32 patients). Successful recanalization of basilar artery occlusion was achieved in 24 patients (46.2%), and partial recanalization was achieved in 16 patients (30.7%). The rate of recanalization was 76.9%. NIHSS scores less than 14, treatment time window less than 24 hours, and a good recanalization were markedly correlated with good clinical prognosis. NIHSS scores less than 14 and treatment time window less than 24 hours were significantly correlated with recanalization. NIHSS scores less than 14 and good recanalization could act as independent predictors for clinical prognosis. Conclusions NIHSS scores less than 14 on admission and successful recanalization can predict favorable outcome for patients with basilar artery occlusion. This study shows that intraarterial thrombolysis and stent placement may be a useful treatment for acute basilar artery occlusion.
- Subjects :
- Adult
Male
medicine.medical_specialty
China
Time Factors
Intraarterial thrombolysis
Risk Assessment
Severity of Illness Index
Disability Evaluation
Fibrinolytic Agents
Modified Rankin Scale
Risk Factors
medicine
Odds Ratio
Vertebrobasilar Insufficiency
Humans
Radiology, Nuclear Medicine and imaging
Thrombolytic Therapy
cardiovascular diseases
Survival rate
Aged
Retrospective Studies
Urokinase
medicine.diagnostic_test
business.industry
Basilar artery occlusion
Digital subtraction angiography
Middle Aged
Combined Modality Therapy
Urokinase-Type Plasminogen Activator
Recombinant Proteins
Surgery
Stroke
Survival Rate
Stent placement
Logistic Models
Treatment Outcome
Injections, Intra-Arterial
Tissue Plasminogen Activator
Acute Disease
Female
Stents
Cardiology and Cardiovascular Medicine
business
TIMI
Angioplasty, Balloon
medicine.drug
Subjects
Details
- ISSN :
- 15357732
- Volume :
- 21
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of vascular and interventional radiology : JVIR
- Accession number :
- edsair.doi.dedup.....1228edb9dcaeacab9d3331c7b16c8e5a