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Lung cancer in patients with idiopathic pulmonary fibrosis: A retrospective multicentre study in Europe
- Source :
- Karampitsakos, T, Spagnolo, P, Mogulkoc, N, Wuyts, W A, Tomassetti, S, Bendstrup, E, Molina-Molina, M, Manali, E D, Unat, Ö S, Bonella, F, Kahn, N, Kolilekas, L, Rosi, E, Gori, L, Ravaglia, C, Poletti, V, Daniil, Z, Prior, T S, Papanikolaou, I C, Aso, S, Tryfon, S, Papakosta, D, Tzilas, V, Balestro, E, Papiris, S, Antoniou, K, Bouros, D, Wells, A, Kreuter, M & Tzouvelekis, A 2023, ' Lung cancer in patients with idiopathic pulmonary fibrosis : A retrospective multicentre study in Europe ', Respirology, vol. 28, no. 1, pp. 56-65 . https://doi.org/10.1111/resp.14363
- Publication Year :
- 2022
-
Abstract
- Background and Objective: There remains a paucity of large databases for patients with idiopathic pulmonary fibrosis (IPF) and lung cancer. We aimed to create a European registry. Methods: This was a multicentre, retrospective study across seven European countries between 1 January 2010 and 18 May 2021. Results: We identified 324 patients with lung cancer among 3178 patients with IPF (prevalence = 10.2%). By the end of the 10 year-period following IPF diagnosis, 26.6% of alive patients with IPF had been diagnosed with lung cancer. Patients with IPF and lung cancer experienced increased risk of all-cause mortality than IPF patients without lung cancer (HR: 1.51, [95% CI: 1.22–1.86], p < 0.0001). All-cause mortality was significantly lower for patients with IPF and lung cancer with a monocyte count of either
Details
- ISSN :
- 14401843
- Volume :
- 28
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Respirology (Carlton, Vic.)REFERENCES
- Accession number :
- edsair.doi.dedup.....1278951145af093d4710bbdff4fd874b
- Full Text :
- https://doi.org/10.1111/resp.14363