Renal Support for Pediatric Patients With Acute Kidney Injury After Cardiac Surgery. What Do We Know Now?

81 children with a mean age of 50-54 months who received continuous renal replacement therapy (CRRT) after CS. These children had a higher mortality rate (43%) than those who received CRRT for noncardiac causes (4%). There were 14 patients on ECLS with 3 of them having the CRRT circuit directly connecting to the ECLS circuit. CRRT was initiated when the fluid balance was positive and there was oliguria, or a serum creatinine concentration double that of normal levels for age. Compared with patients receiving CRRT for other causes, those with CS had a higher incidence of CRRT, lower blood pressure, a longer duration of CRRT, and more frequent need for mechanical ventilation. Risk factors associated with mortality were hypotension at the start of CRRT, Pediatric Risk of Mortality Score21, and the use of hemofiltration.