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Draft genome sequence of a Kluyvera intermedia isolate from a patient with a pancreatic abscess

Authors :
Louise B. Christensen
Heidi Gumpert
Thomas Arn Hansen
Kristian Schønning
Henrik Westh
Peder Worning
Roland Thele
Source :
Journal of global antimicrobial resistance. 10
Publication Year :
2017

Abstract

The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sensitive to Danish-registered antibiotics although it had a fosA-like gene in the genome. There were nine contigs that aligned to a plasmid, and these contigs contained several heavy metal resistance gene homologues. Furthermore, a prophage was discovered in the genome. WGS represents an efficient tool for monitoring Kluyvera spp. and its role as a reservoir of multidrug resistance. Therefore, this susceptible K. intermedia genome has many characteristics that allow comparison of resistant K. intermedia that might be discovered in the future.

Details

ISSN :
22137173
Volume :
10
Database :
OpenAIRE
Journal :
Journal of global antimicrobial resistance
Accession number :
edsair.doi.dedup.....13e315028ec8510921f90aec9d93c263