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Optical coherence tomography angiography of myopic choroidal neovascularisation
- Source :
- The British journal of ophthalmology. 101(5)
- Publication Year :
- 2016
-
Abstract
- Background/aims To describe the morphological features of choroidal neovascularisation (CNV) and to report the ability of optical coherence tomography angiography (OCT-A) to detect the presence of myopic CNV by means of this new technique. Methods Myopic CNV cases were individuated from a pool of patients with pathological myopia consecutively presenting between October 2015 and March 2016. OCT-A images were assessed for classification of morphological features, and to estimate sensitivity and specificity. Results Thirty-six eyes of 28 consecutive patients with myopic CNV were included. In 4 out of 36 eyes it was not possible to classify the CNV ‘shape’, ‘core’, ‘margin’ and ‘appearance’ because the vascular network was not clearly visualised due to the poor quality of the examination. CNV shape on OCT-A was rated as circular in 9 eyes and irregular in 23 eyes. CNV core was visible in 11 eyes. CNV margin was considered as well defined in 16 eyes and poorly defined in 16 eyes. CNV appearance showed an ‘interlacing’ aspect in 16 eyes and a ‘tangled’ aspect in the other 16 eyes. A total of 11 CNVs were defined as active, 9 of which (81.8%) were interlacing, while a total of 21 were inactive, 14 of which (66.7%) were tangled. OCT-A sensitivity turned out to be 90.48% and specificity was 93.75%. Conclusions We describe the OCT-A features of myopic CNV secondary to pathological myopia and demonstrate its high sensitivity and specificity for neovascular detection. Qualitative evaluation of OCT-A characteristics may allow one to recognise different patterns, possibly corresponding to different degrees of neovascular activity.
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
genetic structures
Visual Acuity
Sensitivity and Specificity
Poor quality
Retina
Imaging
03 medical and health sciences
Cellular and Molecular Neuroscience
0302 clinical medicine
Ophthalmology
medicine
Humans
Fluorescein Angiography
Aged
Aged, 80 and over
Neovascularisation
business.industry
Choroid
Pathological myopia
Macula
Optical coherence tomography angiography
Middle Aged
eye diseases
Sensory Systems
Choroidal Neovascularization
Surgery
030104 developmental biology
Vascular network
Myopic choroidal neovascularisation
Myopia, Degenerative
030221 ophthalmology & optometry
Female
sense organs
Diagnostic tests/Investigation
business
Tomography, Optical Coherence
Subjects
Details
- ISSN :
- 14682079
- Volume :
- 101
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- The British journal of ophthalmology
- Accession number :
- edsair.doi.dedup.....142217daab803d29b895009e5642e54c