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Association between comorbidities and absence of chest pain in acute coronary syndrome with in-hospital outcome
- Source :
- International Journal of Cardiology. 217:S37-S43
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Background To evaluate the impact of comorbidities on the management and outcomes of acute coronary syndrome (ACS) patients without chest pain/discomfort (i.e. ACS without typical presentation). Methods Of the 11,458 ACS patients, enrolled by the International Survey of Acute Coronary Syndrome in Transitional Countries (ISACS-TC; ClinicalTrials.gov: NCT01218776), 8.7% did not have typical presentation at the initial evaluation, and 40.2% had comorbidities. The odds of atypical presentation increased proportionally with the number of comorbidities (odds ratio [OR]: 1, no-comorbid; OR: 1.64, 1 comorbidity; OR: 2.52, 2 comorbidities; OR: 4.57, ≥ 3 comorbidities). Results Stratifying the study population by the presence/absence of comorbidities and typical presentation, we found a decreasing trend for use of medications and percutaneous intervention (OR: 1, typical presentation and no-comorbidities; OR: 0.70, typical presentation and comorbidities; OR: 0.23, atypical presentation and no-comorbidities; OR: 0.18, atypical presentation and comorbidities). On the opposite, compared with patients with typical presentation and no-comorbidities (OR: 1, referent), there was an increasing trend (p
- Subjects :
- Male
Chest Pain
Acute coronary syndrome
medicine.medical_specialty
Percutaneous
Heart failure
Comorbidity
030204 cardiovascular system & hematology
Chest pain
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Risk Factors
Chronic kidney disease
Internal medicine
mental disorders
Odds Ratio
medicine
Humans
Hospital Mortality
Registries
030212 general & internal medicine
Acute Coronary Syndrome
Intensive care medicine
Stroke
Aged
Aged, 80 and over
business.industry
Cardiovascular Agents
Odds ratio
Middle Aged
medicine.disease
3. Good health
Female
Presentation (obstetrics)
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 01675273
- Volume :
- 217
- Database :
- OpenAIRE
- Journal :
- International Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....147d986870253da1a8fb706cbc47c4ab