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Robot-assisted Minimally Invasive Thoracolaparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer : A Randomized Controlled Trial
Robot-assisted Minimally Invasive Thoracolaparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer : A Randomized Controlled Trial
- Source :
- Annals of Surgery, 269(4), 621. Lippincott Williams and Wilkins
- Publication Year :
- 2019
-
Abstract
- BACKGROUND: The standard curative treatment for patients with esophageal cancer is perioperative chemotherapy or preoperative chemoradiotherapy followed by open transthoracic esophagectomy (OTE). Robot-assisted minimally invasive thoracolaparoscopic esophagectomy (RAMIE) may reduce complications. METHODS: A single-center randomized controlled trial was conducted, assigning 112 patients with resectable intrathoracic esophageal cancer to either RAMIE or OTE. The primary endpoint was the occurrence of overall surgery-related postoperative complications (modified Clavien-Dindo classification grade 2-5). RESULTS: Overall surgery-related postoperative complications occurred less frequently after RAMIE (59%) compared to OTE (80%) [risk ratio with RAMIE (RR) 0.74; 95% confidence interval (CI), 0.57-0.96; P = 0.02]. RAMIE resulted in less median blood loss (400 vs 568 mL, P
- Subjects :
- Male
medicine.medical_specialty
Esophageal Neoplasms
medicine.medical_treatment
Transthoracic esophagectomy
law.invention
03 medical and health sciences
esophageal carcinoma
0302 clinical medicine
Postoperative Complications
Randomized controlled trial
Robotic Surgical Procedures
law
medicine
Thoracoscopy
Humans
robot assisted
Prospective Studies
esophageal cancer
Laparoscopy
Prospective cohort study
Minimally invasive esophagectomy
Aged
Preoperative chemoradiotherapy
medicine.diagnostic_test
business.industry
Esophageal cancer
Middle Aged
medicine.disease
robot-assisted minimally invasive thoracolaparoscopic esophagectomy
Surgery
Esophagectomy
030220 oncology & carcinogenesis
minimally invasive
030211 gastroenterology & hepatology
Female
business
Subjects
Details
- Language :
- English
- ISSN :
- 00034932
- Volume :
- 269
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Annals of Surgery
- Accession number :
- edsair.doi.dedup.....14bad74ad75c12e0c7eedfdceccfb931
- Full Text :
- https://doi.org/10.1097/sla.0000000000003031