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Robot-assisted Minimally Invasive Thoracolaparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer : A Randomized Controlled Trial

Robot-assisted Minimally Invasive Thoracolaparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer : A Randomized Controlled Trial

Authors :
Sylvia van der Horst
Jelle P. Ruurda
Pieter C. van der Sluis
Lodewijk A.A. Brosens
Inne H.M. Borel Rinkes
Hans C. A. Joore
Anne M. May
Nadia Haj Mohammad
Stella Mook
Christiaan C. Kroese
Frank P. Vleggaar
Carlo Schippers
Richard van Hillegersberg
Source :
Annals of Surgery, 269(4), 621. Lippincott Williams and Wilkins
Publication Year :
2019

Abstract

BACKGROUND: The standard curative treatment for patients with esophageal cancer is perioperative chemotherapy or preoperative chemoradiotherapy followed by open transthoracic esophagectomy (OTE). Robot-assisted minimally invasive thoracolaparoscopic esophagectomy (RAMIE) may reduce complications. METHODS: A single-center randomized controlled trial was conducted, assigning 112 patients with resectable intrathoracic esophageal cancer to either RAMIE or OTE. The primary endpoint was the occurrence of overall surgery-related postoperative complications (modified Clavien-Dindo classification grade 2-5). RESULTS: Overall surgery-related postoperative complications occurred less frequently after RAMIE (59%) compared to OTE (80%) [risk ratio with RAMIE (RR) 0.74; 95% confidence interval (CI), 0.57-0.96; P = 0.02]. RAMIE resulted in less median blood loss (400 vs 568 mL, P

Details

Language :
English
ISSN :
00034932
Volume :
269
Issue :
4
Database :
OpenAIRE
Journal :
Annals of Surgery
Accession number :
edsair.doi.dedup.....14bad74ad75c12e0c7eedfdceccfb931
Full Text :
https://doi.org/10.1097/sla.0000000000003031