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Comparison of chemical constituents among licorice, roasted licorice, and roasted licorice with honey
- Source :
- Journal of Natural Medicines. 72:80-95
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- Licorice (root and rhizome of Glycyrrhiza uralensis Fisch.) is sometimes used as crude drug after processing. In this report, we prepared roasted licorice with or without honey using 3 lots of crude drug samples derived from wild G. uralensis, and analyzed the constituents in unprocessed, roasted, and honey-roasted licorice samples by high performance liquid chromatography–electrospray ionization-ion trap-time of flight mass spectrometry (HPLC–ESI-IT-TOF-MSn) with principal component analysis. We found that the areas of 41 peaks were noticeably changed by processing. Among them, the areas of 12 peaks, viz. isoliquiritin, isoliquiritigenin, glucoisoliquiritin, 6″-O-acetylisoliquiritin, 6″-O-acetylisoliquiritin apioside, glycyrrhetinic acid 3-O-glucuronide, 5 kinds of sugar-derivatives and one compound whose molecular weight was 386 Da were increased by roasting in all 3 lots, and those peak areas were increased by higher heating temperatures. Among the increased peaks, 3 kinds of sugar-derivatives had larger areas, and 6″-O-acetylisoliquiritin had lower areas than those in honey-roasted licorice. Those sugar-derivatives were the only characteristics differing between honey-roasted licorice and roasted licorice. Meanwhile, the areas of 9 peaks, four of them identified as 6″-O-acetylliquiritin, 6″-O-acetylliquiritin apioside, formononetin and gancaonin l, were decreased by roasting in all 3 lots, but there were no differences between roasted licorice with or without honey. Those compounds whose amounts were changed by processing could be used as markers for the quality control of roasted and honey-roasted licorice.
- Subjects :
- Principal Component Analysis
Chromatography
biology
Chemistry
010401 analytical chemistry
Glycyrrhiza uralensis
Pharmacology toxicology
Honey
Crude drug
biology.organism_classification
030226 pharmacology & pharmacy
01 natural sciences
0104 chemical sciences
Rhizome
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Chemical constituents
Glycyrrhiza
Molecular Medicine
Formononetin
Food science
Chromatography, High Pressure Liquid
Isoliquiritigenin
Roasting
Subjects
Details
- ISSN :
- 18610293 and 13403443
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- Journal of Natural Medicines
- Accession number :
- edsair.doi.dedup.....14c308f4bcd6c6a8af3c99364e67253f