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Paper microfluidics for nucleic acid amplification testing (NAAT) of infectious diseases
- Source :
- Lab on a Chip, Lab on a Chip, Royal Society of Chemistry, 2017, 17 (14), pp.2347-2371. ⟨10.1039/c7lc00013h⟩, Lab on a Chip, 2017, 17 (14), pp.2347-2371. ⟨10.1039/c7lc00013h⟩
- Publication Year :
- 2017
- Publisher :
- HAL CCSD, 2017.
-
Abstract
- International audience; The diagnosis of infectious diseases is entering a new and interesting phase. Technologies based on paper microfluidics, coupled to developments in isothermal amplification of Nucleic Acids (NAs) raise opportunities for bringing the methods of molecular biology in the field, in a low setting environment. A lot of work has been performed in the domain over the last few years and the landscape of contributions is rich and diverse. Most often, the level of sample preparation differs, along with the sample nature, the amplification and detection methods, and the design of the device, among other features. In this review, we attempt to offer a structured description of the state of the art. The domain is not mature and there exist bottlenecks that hamper the realization of Nucleic Acid Amplification Tests (NAATs) complying with the constraints of the field in low and middle income countries. In this domain however, the pace of progress is impressively fast. This review is written for a broad Lab on a Chip audience.
- Subjects :
- Paper
[SDV.BIO]Life Sciences [q-bio]/Biotechnology
Microfluidics
Biomedical Engineering
Loop-mediated isothermal amplification
Bioengineering
Nanotechnology
02 engineering and technology
Biology
01 natural sciences
Biochemistry
Communicable Diseases
law.invention
Domain (software engineering)
law
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Lab-On-A-Chip Devices
Nucleic Acid Amplification Tests
Humans
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
010401 analytical chemistry
General Chemistry
Nucleic acid amplification technique
Equipment Design
Lab-on-a-chip
Microfluidic Analytical Techniques
021001 nanoscience & nanotechnology
Data science
0104 chemical sciences
3. Good health
Molecular Diagnostic Techniques
Low and middle income countries
Nucleic acid
0210 nano-technology
Nucleic Acid Amplification Techniques
Subjects
Details
- Language :
- English
- ISSN :
- 14730197 and 14730189
- Database :
- OpenAIRE
- Journal :
- Lab on a Chip, Lab on a Chip, Royal Society of Chemistry, 2017, 17 (14), pp.2347-2371. ⟨10.1039/c7lc00013h⟩, Lab on a Chip, 2017, 17 (14), pp.2347-2371. ⟨10.1039/c7lc00013h⟩
- Accession number :
- edsair.doi.dedup.....1504cb2ef05c9fb8f90900d2867a36e2