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Evaluation of foveal photoreceptor layer in eyes with macular edema associated with branch retinal vein occlusion after ozurdex treatment
- Source :
- International Ophthalmology. 37:333-339
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- The aim of this study was to evaluate the central retinal thickness (CRT), outer nuclear layer thickness (ONLT), photoreceptor layer thickness (PLT), photoreceptor layer integrity, and the correlation between visual acuity and PLT in eyes with branch retinal vein occlusion (BRVO) 2 months after treatment with intravitreal dexamethasone implant (Ozurdex; Allergan, Inc, Irvine, CA). In this prospective study, 32 eyes of 32 patients were enrolled. A single injection of Ozurdex was administered to all the patients. CRT, ONLT, and PLT were measured using spectral-domain optical coherence tomography before and 2 months after the injection. Best-corrected visual acuity (BCVA [logMAR]) and photoreceptor cell integrity were also evaluated. The average CRT, ONLT, PLT, and BCVA values for the sample group before the treatment were as follows: 707 ± 261, 608 ± 288, 70 ± 25, and 0.96 ± 0.22 µm, respectively. The average CRT, ONLT, PLT, and BCVA values for the sample group 2 months after the Ozurdex injection were as follows: 299 ± 149, 211 ± 138, 77 ± 20, and 0.63 ± 0.30 µm, respectively (p
- Subjects :
- Male
Fovea Centralis
medicine.medical_specialty
Time Factors
Visual acuity
genetic structures
Fundus Oculi
Dexamethasone
Macular Edema
Photoreceptor cell
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Ophthalmology
Retinal Vein Occlusion
medicine
Humans
Prospective Studies
Fluorescein Angiography
Outer nuclear layer
Glucocorticoids
Macular edema
Aged
Aged, 80 and over
Drug Implants
medicine.diagnostic_test
business.industry
Fovea centralis
Retinal
Middle Aged
medicine.disease
Fluorescein angiography
eye diseases
Treatment Outcome
medicine.anatomical_structure
chemistry
Intravitreal Injections
030221 ophthalmology & optometry
Branch retinal vein occlusion
Optometry
Female
sense organs
medicine.symptom
business
Tomography, Optical Coherence
030217 neurology & neurosurgery
Follow-Up Studies
Photoreceptor Cells, Vertebrate
Subjects
Details
- ISSN :
- 15732630 and 01655701
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- International Ophthalmology
- Accession number :
- edsair.doi.dedup.....150cc3d2f82bea6b4c364ce38b28f368