Additional file 1: of On the association analysis of CNV data: a fast and robust family-based association method

A complete report for all experiments performed for this work. Text 1. Rao’s score test statistic with the expected copy number. Text 2. Rao’s score test statistic with the probe intensity measurements. Figure S1. Results of the clustering analysis with family samples (A) and cohort samples (B). Figure S2. Schematic representation of the strategy for the CNV analysis. Figure S3. Validation results. Figure S4. Validation results of replication samples by TaqMan qPCR experiment. Table S1. Specification of parameters for the signal model used in the simulation studies. Table S2. Primer information for CNV validation. Table S3. Accuracy of copy number clusters identified with PedCNV. Table S4. Accuracy of copy number clusters identified with CNVtools. Table S5. Accuracy of copy number estimated with silhouette score. Table S6. Empirical type 1 error estimates when M = 6. Table S7. Empirical power estimates when M = 6. Table S8. Empirical power estimates of T 1 and T 1 * which use the expected copy number and the most probable copy number respectively. Table S9. Estimated parameters of T 1 and T 1 * which use the expected copy number and the most probable copy number respectively. (PDF 814 kb)