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Haptoglobin phenotype in age-related macular degeneration patients
Haptoglobin phenotype in age-related macular degeneration patients
- Source :
- American journal of ophthalmology. 136(5)
- Publication Year :
- 2003
-
Abstract
- Purpose To investigate a possible role of the haptoglobin phenotype in the development of exudative age-related macular degeneration (AMD) in human subjects. Design Prospective, observational, comparative population study. Methods The study was carried out in an institutional setting. All patients referred because of exudative AMD in one eye during an 18-month period were included in the study group. A group of patients treated for other ocular diseases and not having AMD in either eye served as control. Haptoglobin phenotype was determined from a blood sample drawn from each patient in both the study and control groups. The main outcome measure was the distribution of the haptoglobin phenotype in the study and control group. Results One hundred eighty-five participants were included in the study. Ninety-eight had exudative AMD, and 87 were AMD-free. The difference between the study and control groups in distribution of the haptoglobin phenotype was found to be statistically insignificant. Conclusions Our results suggest that the haptoglobin phenotype has no effect on the prevalence of exudative AMD.
- Subjects :
- Male
medicine.medical_specialty
Pathology
genetic structures
Eye disease
Macular Degeneration
Internal medicine
medicine
Prevalence
Humans
Prospective Studies
Aged
biology
Haptoglobins
business.industry
Haptoglobin
Macular degeneration
medicine.disease
Phenotype
eye diseases
Ophthalmology
biology.protein
Maculopathy
Population study
Observational study
Female
sense organs
business
Retinopathy
Subjects
Details
- ISSN :
- 00029394
- Volume :
- 136
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- American journal of ophthalmology
- Accession number :
- edsair.doi.dedup.....151cd7c69fa1db38541a2b7ded08a2fe