Additional file 1 of K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway

Additional file 1: Table S1. List and sequences of qPCR primers for mRNA expression. Figure S1. The CHI3L1 levels (A) in serum and (B) in brain were assessed using the specific ELISA kits. Figure S2. PTX3 is associated with CHI3L1 (A) Gene network analysis associated with CHI3L1 was carried out using the web-based analysis tool. The mRNA expression level of Chi3l1, Cd163, Ctsd, Ido1, and Ptx3 were assessed by qRT-PCR. (B) BV-2 cells were transfected with CHI3L1-expression vector. (C) BV-2 cells were transfected with CHI3L1 siRNA (40 nM).