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Content of Health Economics Analysis Plans (HEAPs) for Trial-Based Economic Evaluations: Expert Delphi Consensus Survey

Authors :
Sara T Brookes
Ewan Gray
Sarah Wordsworth
Colin Ridyard
Borislava Mihaylova
Dyfrig A. Hughes
Tracey Sach
Stavros Petrou
Joanna Thorn
William Hollingworth
Charlotte F Davies
Edward C. F. Wilson
Sian Noble
Melina Dritsaki
Source :
Value in Health, Thorn, J C, Davies, C F, Brookes, S T, Noble, S M, Dritsaki, M, Gray, E, Hughes, D A, Mihaylova, B, Petrou, S, Ridyard, C, Sach, T, Wilson, E C F, Wordsworth, S & Hollingworth, W 2021, ' Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations : expert Delphi consensus survey ', Value in Health, vol. 24, no. 4, pp. 539-547 . https://doi.org/10.1016/j.jval.2020.10.002
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

Objectives Health economics analysis plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials. Methods A list of potential items for inclusion was developed by examining existing HEAPs. An electronic Delphi survey was conducted among professional health economists. Respondents were asked to rate potential items from 1 (least important) to 9 (most important), suggest additional items, and comment on proposed items (round 1). A second survey (round 2) was emailed to participants, including the participant’s own scores from round 1 along with summary results from the whole panel; participants were asked to rerate each item. Consensus criteria for inclusion in the final list were predefined as >70% of participants rating an item 7-9 and<br />Highlights • Health economics analysis plans (HEAPs) are becoming best practice for economic evaluations conducted alongside randomized controlled trials; however, they are currently implemented inconsistently. • This study used Delphi consensus techniques to identify a list of items that should be included in a HEAP. • A standardized HEAP will contribute to the transparency and reproducibility of economic evaluations and to the minimization of bias.

Details

ISSN :
10983015
Volume :
24
Database :
OpenAIRE
Journal :
Value in Health
Accession number :
edsair.doi.dedup.....156a9d9b24a5ffcd528e1a96937338a4
Full Text :
https://doi.org/10.1016/j.jval.2020.10.002