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Trend of clinical outcome and surrogate markers during titration of β-blocker in heart failure patients with reduced ejection fraction: relevance of achieved heart rate and β-blocker dose
- Source :
- Circulation journal : official journal of the Japanese Circulation Society. 77(4)
- Publication Year :
- 2012
-
Abstract
- BACKGROUND:The aim of this study was to examine trends of clinical outcome and to clarify surrogate markers when titrating β-blocker in heart failure patients with reduced left ventricular ejection fraction (HFrEF, LVEF
- Subjects :
- Male
medicine.medical_specialty
medicine.drug_class
Carbazoles
Propanolamines
Heart Rate
Internal medicine
Heart rate
medicine
Humans
Carvedilol
Beta blocker
Aged
Heart Failure
Ejection fraction
Dose-Response Relationship, Drug
business.industry
Proportional hazards model
Hazard ratio
Stroke Volume
General Medicine
Middle Aged
medicine.disease
Dose–response relationship
Heart failure
Cardiology
Adrenergic alpha-1 Receptor Antagonists
Female
Cardiology and Cardiovascular Medicine
business
Biomarkers
medicine.drug
Subjects
Details
- ISSN :
- 13474820
- Volume :
- 77
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Circulation journal : official journal of the Japanese Circulation Society
- Accession number :
- edsair.doi.dedup.....1598d68b503a0418edfac82f6586ab5f