Variability of T1 in purpose recruited normal volunteers and patients as a function of shim (B0), flip angle (B1) and myocardial sector at 3T

Background The purpose of this study was to assess inter-subject and spatial variability of T1 measurements in normal volunteers and investigate potential reasons for non-uniform T1 measurements such as off resonance and imperfect flip angle at 3T. A comparison group of patients with normal studies was used to assess how well findings translate to the clinical setting.