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Does advanced age affect treatment of early glottic carcinoma?
- Source :
- European Annals of Otorhinolaryngology, Head and Neck Diseases, European Annals of Otorhinolaryngology, Head and Neck Diseases, Elsevier Masson, 2021, 138 (2), pp.68-72. ⟨10.1016/j.anorl.2020.06.021⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; Aims: Early glottic carcinoma is currently managed by radiation therapy or endoscopic surgery. Both are effective in elderly patients, but their respective indications are poorly determined. The present study assessed our management of very elderly patients with early glottic carcinoma. Material and methods: A retrospective single-center study included all patients aged 75 years and older at diagnosis, treated by radiation therapy or endoscopic surgery with curative intent for T1 or T2 glottic carcinoma between 2004 and 2018. Results: Records of 33 patients (27 men and 6 women; mean age, 82.2 years (range, 76.1-93.1 years)) were reviewed. 24 patients received radiation therapy and 9 endoscopic resection. The only factor for choice of treatment was anterior commissure involvement. Overall survival was 87% at 2 years and 62% at 5 years. 19% of patients relapsed within 5 years and had to undergo further treatment. There were no treatment-related deaths. Radiation therapy was associated with more acute local complications, with two temporary treatment interruptions and one uncompleted treatment. Surgical treatment was more likely to result in dysphonia, found in 80% of cases. Conclusion: Treatment of early glottic cancer in elderly subjects can consist in either radiotherapy or endoscopic surgery. Age should not affect management. Surgical treatment is shorter and better tolerated, although with poorer vocal outcome, and may be preferred in the most comorbid patients.
- Subjects :
- Male
Early glottic cancer
Glottis
medicine.medical_specialty
medicine.medical_treatment
[SDV]Life Sciences [q-bio]
Laryngectomy
Anterior commissure
Affect (psychology)
03 medical and health sciences
0302 clinical medicine
Overall survival
medicine
Humans
Endoscopic resection
030223 otorhinolaryngology
Surgical treatment
Laryngeal Neoplasms
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Carcinoma
Mean age
3. Good health
Surgery
Radiation therapy
Elderly patients
Otorhinolaryngology
Glottic cancer
030220 oncology & carcinogenesis
Endoscopic cordectomy
Female
business
Subjects
Details
- Language :
- English
- ISSN :
- 18797296 and 1879730X
- Database :
- OpenAIRE
- Journal :
- European Annals of Otorhinolaryngology, Head and Neck Diseases, European Annals of Otorhinolaryngology, Head and Neck Diseases, Elsevier Masson, 2021, 138 (2), pp.68-72. ⟨10.1016/j.anorl.2020.06.021⟩
- Accession number :
- edsair.doi.dedup.....16af39e6cbb13908f683039aefb38b89