Back to Search
Start Over
Fluorescent glycoconjugates and their applications
- Source :
- Chemical Society Reviews, Chemical Society Reviews, Royal Society of Chemistry, 2020, 49 (2), pp.593-641. ⟨10.1039/C8CS00118A⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- International audience; Glycoconjugates and their applications as lectin ligands in biology has been thoroughly investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent molecules were limited essentially to their ability to bind to their receptors with high selectivity and/or avidity. The present review will focus on multivalent glycoconjugates displaying an additional capability such as fluorescence properties for applications toward imaging of cancer cells, detection of proteins or pathogens but also for drug delivery systems toward targeted cancer therapy. This review is a collection of research articles discussed in the context of the structural features of the fluorescent glycoconjugates organized according to their fluorescent core scaffold and with their representative applications.
- Subjects :
- Glycoconjugate
High selectivity
Cancer therapy
Antineoplastic Agents
Context (language use)
010402 general chemistry
01 natural sciences
Fluorescence
Drug Delivery Systems
Cell Line, Tumor
Neoplasms
Humans
[CHIM]Chemical Sciences
Avidity
Fluorescent Dyes
chemistry.chemical_classification
biology
010405 organic chemistry
[CHIM.ORGA]Chemical Sciences/Organic chemistry
Lectin
General Chemistry
3. Good health
0104 chemical sciences
Biochemistry
chemistry
Drug delivery
biology.protein
Glycoconjugates
Subjects
Details
- Language :
- English
- ISSN :
- 03060012 and 14604744
- Database :
- OpenAIRE
- Journal :
- Chemical Society Reviews, Chemical Society Reviews, Royal Society of Chemistry, 2020, 49 (2), pp.593-641. ⟨10.1039/C8CS00118A⟩
- Accession number :
- edsair.doi.dedup.....17b2c38117d568089044fffed77205cd
- Full Text :
- https://doi.org/10.1039/C8CS00118A⟩