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Differences in Optical Coherence Tomography Assessment of Bruch Membrane Opening Compared to Stereoscopic Photography for Estimating Cup-to-Disc Ratio
- Source :
- American Journal of Ophthalmology. 184:34-41
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- To compare the vertical and horizontal cup-to-disc ratio (VCDR, HCDR) by an updated optical coherence tomography (OCT) Bruch membrane opening (BMO) algorithm and stereoscopic optic disc photograph readings by glaucoma specialists.Reliability analysis.A total of 195 eyes (116 glaucoma and 79 glaucoma suspect) of 99 patients with stereoscopic photographs and OCT scans of the optic discs taken during the same visit were compared. Optic disc photographs were read by 2 masked glaucoma specialists for VCDR and HCDR estimation. Intraclass correlation coefficient (ICC) and Bland-Altman plots were used to assess the agreement between photograph reading and OCT in estimating CDR.OCT images computed significantly larger VCDR and HCDR than photograph reading before and after stratifying eyes based on disc size (P.001). The difference in CDR estimates between the 2 methods was equal to or greater than 0.2 in 29% and 35% of the eyes for VCDR and HCDR, respectively, with a mean difference of 0.3 in each case. The ICCs between the readers and OCT ranged between 0.50 and 0.63. The size of disagreement in VCDR correlated weakly with cup area in eyes with medium (rOCT and photograph reading by clinicians agree poorly in CDR assessment. The difference in VCDR between the 2 methods was depended on cup area in medium and large discs. These differences should be considered when making conclusions regarding CDRs in clinical practice.
- Subjects :
- Male
0301 basic medicine
medicine.medical_specialty
Intraocular pressure
genetic structures
Intraclass correlation
Optic Disk
Glaucoma
Stereoscopy
Cup-to-disc ratio
Severity of Illness Index
law.invention
03 medical and health sciences
0302 clinical medicine
Optics
Optical coherence tomography
law
Ophthalmology
Optic Nerve Diseases
medicine
Humans
Intraocular Pressure
Retrospective Studies
medicine.diagnostic_test
business.industry
Photography
Reproducibility of Results
Middle Aged
medicine.disease
eye diseases
030104 developmental biology
medicine.anatomical_structure
030221 ophthalmology & optometry
Female
Bruch Membrane
sense organs
business
Glaucoma, Open-Angle
Tomography, Optical Coherence
Optic disc
Subjects
Details
- ISSN :
- 00029394
- Volume :
- 184
- Database :
- OpenAIRE
- Journal :
- American Journal of Ophthalmology
- Accession number :
- edsair.doi.dedup.....17b461920a1078c4af2970852fc832be