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Impact of adrenomedullin levels on clinical risk stratification and outcome in subarachnoid haemorrhage
- Source :
- European journal of clinical investigationREFERENCES. 50(11)
- Publication Year :
- 2019
-
Abstract
- PURPOSE To use classification tree analysis to identify risk factors for nonsurvival in a neurological patients with subarachnoid haemorrhage (SAH) and to propose a clinical model for predicting of mortality. METHODS Prospective study of SAH admitted to a Critical Care Department and Stroke Unit over a 2-year period. Middle region of pro-ADM plasma levels (MR-proADM) was measured in EDTA plasma within the first 24 hours of hospital admission using the automatic immunofluorescence test. A regression tree was made to identify prognostic models for the development of mortality at 90 days. RESULTS Ninety patients were included. The mean MR-proADM plasma value in the samples analysed was 0.78 ± 0.41 nmol/L. MR-proADM plasma levels were significantly associated with mortality at 90 days (1.05 ± 0.51 nmol/L vs 0.64 ± 0.25 nmol/L; P
- Subjects :
- Adult
Male
medicine.medical_specialty
Clinical Biochemistry
030204 cardiovascular system & hematology
Biochemistry
Risk Assessment
Severity of Illness Index
03 medical and health sciences
Adrenomedullin
Young Adult
0302 clinical medicine
Internal medicine
medicine
Risk of mortality
Humans
030212 general & internal medicine
Prospective Studies
Mortality
Protein Precursors
Prospective cohort study
Stroke
APACHE
Aged
Aged, 80 and over
APACHE II
business.industry
General Medicine
Middle Aged
Subarachnoid Hemorrhage
medicine.disease
Prognosis
Peptide Fragments
Biomarker (medicine)
Subarachnoid haemorrhage
Female
business
Clinical risk factor
Subjects
Details
- ISSN :
- 13652362
- Volume :
- 50
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- European journal of clinical investigationREFERENCES
- Accession number :
- edsair.doi.dedup.....17e47ad10f3df46390cc78a6c221370d