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Livelihood Security and Adherence to Antiretroviral Therapy in Low and Middle Income Settings: A Systematic Review
- Source :
- PLoS ONE, Vol 6, Iss 5, p e18948 (2011), PLoS ONE
- Publication Year :
- 2011
- Publisher :
- Public Library of Science (PLoS), 2011.
-
Abstract
- IntroductionWe sought to examine the association between livelihood security and adherence to antiretroviral therapy (ARVs) in low- and middle-income countries (LIMC).MethodsPerforming a systematic review, we searched, independently and in duplicate, 7 electronic databases and 2 conference websites for quantitative surveys that examined the association between indicators of livelihood security and adherence to ARVs in LIMC between 2000-2010. Criteria for relevance were applied to complete papers (quantitative study with estimates of associations) and quality assessment was conducted on those deemed relevant. We performed three regressions to measure the association between each type of livelihood and adherence.ResultsTwenty original studies and 6 conference abstracts were included, the majority from Africa (n = 16). Seventeen studies and 3 conference abstracts were cross-sectional and 3 studies and 3 abstracts were prospective clinical cohort studies, with considerable variation in quality for studies of each design type. Among the diverse populations represented, we observed considerable variation in associations between measurements of livelihood indicators and increasingly accepted adherence measures, irrespective of study design or quality. A financial capital indicator, financial constraints/payment for ARV medication, was more commonly associated with non-adherence (3/5 studies). A human capital indicator, educational level, was most commonly associated with adherence (11/20 studies).DiscussionAdditional better quality research examining livelihood security is required to inform provision of optimal supports for adherence and mitigation of the impacts of HIV/AIDS.
- Subjects :
- Non-Clinical Medicine
Epidemiology
Cross-sectional study
HIV Infections
Global Health
Medicine
Clinical Epidemiology
Epidemiological Methods
media_common
Multidisciplinary
HIV diagnosis and management
Antivirals
Livelihood
Socioeconomic Aspects of Health
AIDS
Income
Infectious diseases
Health Services Research
Public Health
Guideline Adherence
Research Article
Systematic Reviews
Clinical Research Design
Anti-HIV Agents
Science
media_common.quotation_subject
Sexually Transmitted Diseases
MEDLINE
Viral diseases
Microbiology
Human capital
Infectious Disease Epidemiology
Financial capital
Acquired immunodeficiency syndrome (AIDS)
Virology
Environmental health
Humans
Quality (business)
Biology
Poverty
business.industry
HIV
medicine.disease
Social Epidemiology
Cross-Sectional Studies
Meta-Analyses
business
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....1806e24209528e3418e5365974f4b3b0