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Silybin induces endothelium-dependent vasodilation via TRPV4 channels in mouse mesenteric arteries

Authors :
Xin, Wen
Yidi, Peng
Bohao, Zheng
Shaying, Yang
Jing, Han
Fan, Yu
Tingting, Zhou
Li, Geng
Zhiming, Yu
Lei, Feng
Source :
Hypertension Research. 45:1954-1963
Publication Year :
2022
Publisher :
Springer Science and Business Media LLC, 2022.

Abstract

Silybin is a flavonolignan extracted from the seeds of Silybum marianum that has been used as a dietary supplement for treating hepatic diseases and components of metabolic syndrome such as diabetes, obesity and hypertension. Transient receptor potential vanilloid 4 (TRPV4) channels are Ca

Details

ISSN :
13484214 and 09169636
Volume :
45
Database :
OpenAIRE
Journal :
Hypertension Research
Accession number :
edsair.doi.dedup.....18460331f0c1c51a9a2ed614e5340809