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Cycloartane-type triterpene glycosides from Beesia calthaefolia and their anticomplement activity

Authors :
Jin-Yuan Zhao
Dai-Hong Guo
Hong-Jie Li
Li-Hua Mu
Ping Liu
Source :
Journal of natural medicines. 68(3)
Publication Year :
2013

Abstract

Two new 9,19-cycloartane triterpenes (1, 2), together with three known compounds (3-5), were isolated from the whole plant of Beesia calthaefolia. Their structures were determined by the application of spectroscopic analyses and chemical methods. Compound 1 showed moderate anticomplement activity similar to that of the positive control (rosmarinic acid), while compounds 3 and 4 showed weak activity. The results suggest that 6'-O-(4″-hydroxy-3″-methoxy-benzoyl)-β-D-glucosyl of 9,19-cycloartane-type triterpenoids could be a structure that is essential for anticomplement activity.

Details

ISSN :
18610293
Volume :
68
Issue :
3
Database :
OpenAIRE
Journal :
Journal of natural medicines
Accession number :
edsair.doi.dedup.....18e1ece4ddfa1f8d35d426416fe545f8