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Supplemental Figure 2 from Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma

Authors :
Pasi A. Jänne
David M. Jackman
Geoffrey R. Oxnard
Suzanne E. Dahlberg
Christine Lydon
Mohit Butaney
Jason L. Hornick
Ashley K. Pelton
Scott J. Rodig
Lynette M. Sholl
Antonio Calles
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplemental Figure 2. A, KRAS G12C mutation is the most frequently mutated in smokers while G12D is most common in never-smokers. B and C, Never-smokers were significantly more likely than former or current smokers to have a transition mutation (G>A) rather than transversion mutations known to be smoking-related (G>T or G>C).

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....18e3f79c852edc3b4f79ef8a65b92632
Full Text :
https://doi.org/10.1158/1078-0432.22461309