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Is the Fgap1 mediated response to oxidative stress chemotype dependent in Fusarium graminearum?
- Source :
- FEMS Microbiology Letters, FEMS Microbiology Letters, Wiley-Blackwell, 2016, 363 (2), 7 p. ⟨10.1093/femsle/fnv232⟩
- Publication Year :
- 2015
-
Abstract
- International audience; This study aims to compare the role of the transcription factor Fgap1 in oxidative stress response for two Fusarium graminearum strains belonging to the two chemotypes DON/ADON and NIV/FX. While the response to H2O2 was shown to be chemotype dependent, an opposite result was observed for diamide: whatever the chemotype, the global level of TCTB (i.e. trichothecene B) production was strongly increased by the treatment with diamide. Fgap1 was shown to be involved in this regulation for both chemotypes. Our data show that the response to diamide is mediated by Fgap1 whatever the chemotype of the F. graminearum strains. However, the NIV/FX chemotype has developed higher antioxidant capacities in response to oxidative stress. But when this capacity is overwhelmed by an increment in the H2O2 level, the NIV/FX strains also responds by an increase in toxin accumulation.
- Subjects :
- 0301 basic medicine
Fusarium
Antioxidant
medicine.medical_treatment
[SDV]Life Sciences [q-bio]
Trichothecene
medicine.disease_cause
Microbiology
Fungal Proteins
03 medical and health sciences
mycotoxins
Genetics
medicine
trichothecenes
Molecular Biology
Transcription factor
chemotype
Diamide
Fungal protein
biology
Chemotype
Toxin
Hydrogen Peroxide
biology.organism_classification
Oxidative Stress
030104 developmental biology
Biochemistry
Oxidative stress
Transcription Factors
Subjects
Details
- ISSN :
- 15746968 and 03781097
- Volume :
- 363
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- FEMS microbiology letters
- Accession number :
- edsair.doi.dedup.....1915eed0f3b5475cb20997463bfdd5e7