Back to Search Start Over

Figure S3 from Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase–Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type

Authors :
David G. Huntsman
Yemin Wang
Patrick Pirrotte
Lynn Hoang
Jeffrey M. Trent
Bernard E. Weissman
C. Blake Gilks
Jessica N. McAlpine
Gregg B. Morin
Anthony Karnezis
Friedrich Kommoss
Gian Luca Negri
Shane Colborne
Christine Chow
Angela Cheng
Samuel Leung
David Farnell
Isabel N. Alcazar
Khyatiben V. Pathak
Germain Ho
Shary Yutin Chen
Basile Tessier-Cloutier
Dawn R. Cochrane
Jennifer X. Ji
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Decreased ASS1 expression correlates with CTNNB1 mutation in ENOC and EEC. A, ASS1 mRNA Z-score in 26 cases of ENOC cases described in publication by Wang et al (30). B, ASS1 histoscore distribution in CTNNB1 mutated and wildtype endometroid endometrial and endometrioid ovarian cancers. C, ASS1 mRNA raw counts in the TCGA endometrial cohort as related to CTNNB1 mutation status. P values were calculated using a Wilcoxin rank sum test.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....193a6c2fcc51c10b51dcc6c8f61542b9
Full Text :
https://doi.org/10.1158/1078-0432.22477664