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Characterization of PLLA scaffolds for biomedical applications
- Publication Year :
- 2017
- Publisher :
- Taylor and Francis, 2017.
-
Abstract
- The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs.
- Subjects :
- Pore size
Scaffold
Materials science
Polymers and Plastics
General Chemical Engineering
Nanotechnology
02 engineering and technology
scaffold
010402 general chemistry
01 natural sciences
PLLA
Analytical Chemistry
Tissue engineering
pore size distribution
Chemical Engineering (all)
Porosity
Settore ING-IND/24 - Principi Di Ingegneria Chimica
integumentary system
Low-field NMR
phase separation
021001 nanoscience & nanotechnology
0104 chemical sciences
Characterization (materials science)
Settore ING-IND/22 - Scienza E Tecnologia Dei Materiali
Wound dressing
Drug delivery
0210 nano-technology
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....1948164300fa109286c4c03c0057f594