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Direct Observation of the Orientation Dynamics of Single Protein-Coated Nanoparticles at Liquid/Solid Interfaces
- Source :
- Angewandte Chemie. 126:7071-7075
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- We have observed the rotational dynamics of single protein-coated gold nanorods (AuNRs) on C18-modified silica surfaces in real time by dual-channel polarization dark-field microscopy. Four different rotational states were identified, depending on the apparent strength of interactions between the AuNRs and the surface. The distributions of the states could be regulated by adjusting the salt concentration, and the state transitions were verified by monitoring the entire desorption process of a single AuNR. Our study provides insight into the interfacial orientation and dynamics of nanoparticles and could be useful for in vitro biophysics and the separation of proteins.
- Subjects :
- Nanotubes
Surface Properties
Chemistry
Analytical chemistry
Direct observation
Proteins
Nanoparticle
Serum Albumin, Bovine
General Chemistry
Liquid solid
General Medicine
Silicon Dioxide
Polarization (waves)
Catalysis
Hydrophobic effect
Ammonium Sulfate
Chemical physics
Desorption
Microscopy
Nanoparticles
Nanorod
Gold
alpha-Amylases
Hydrophobic and Hydrophilic Interactions
Subjects
Details
- ISSN :
- 00448249
- Volume :
- 126
- Database :
- OpenAIRE
- Journal :
- Angewandte Chemie
- Accession number :
- edsair.doi.dedup.....19dcee7fd587b1908d437f43242741b8