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Novel Benchmark Values for Redo Liver Transplantation

Authors :
Fariba Abbassi
Daniel Gero
Xavier Muller
Alba Bueno
Wojciech Figiel
Fabien Robin
Sophie Laroche
Benjamin Picard
Sadhana Shankar
Tommy Ivanics
Marjolein van Reeven
Otto B. van Leeuwen
Hillary J. Braun
Diethard Monbaliu
Antoine Breton
Neeta Vachharajani
Eliano Bonaccorsi Riani
Greg Nowak
Robert R. McMillan
Samir Abu-Gazala
Amit Nair
Rocio Bruballa
Flavio Paterno
Deborah Weppler Sears
Antonio D. Pinna
James V. Guarrera
Eduardo de Santibañes
Martin de Santibañes
Roberto Hernandez-Alejandro
Kim Olthoff
R Mark Ghobrial
Bo-Göran Ericzon
Olga Ciccarelli
William C. Chapman
Jean-Yves Mabrut
Jacques Pirenne
Beat Müllhaupt
Nancy L. Ascher
Robert J. Porte
Vincent E. de Meijer
Wojciech G. Polak
Gonzalo Sapisochin
Magdy Attia
Olivier Soubrane
Emmanuel Weiss
René A. Adam
Daniel Cherqui
Karim Boudjema
Krzysztof Zieniewicz
Wayel Jassem
Philipp Dutkowski
Pierre-Alain Clavien
Surgery
Faculteit Medische Wetenschappen/UMCG
Groningen Institute for Organ Transplantation (GIOT)
UCL - SSS/IREC - Institut de recherche expérimentale et clinique
UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation
UCL - (SLuc) Service de chirurgie et transplantation abdominale
Source :
Annals of Surgery, 276(5), 860-867. Lippincott Williams & Wilkins, Annals of Surgery, 276(5), 860-867. LIPPINCOTT WILLIAMS & WILKINS, Annals of Surgery, Vol. 276, no. 5, p. 860-867 (2022)
Publication Year :
2022
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2022.

Abstract

Objective In the era of organ shortage, redo liver transplantation (reLT) is frequently discussed in terms of expected poor outcome, high cost and therefore wasteful resources. However, there is a lack of benchmark data to reliably assess outcomes after reLT. The aim of this study was to define the ideal reLT case, and to establish clinically relevant benchmark values for best achievable outcome in reLT. Methods We collected data on reLT between January 2010 and December 2018 from 22 high volume transplant centers on three continents. Benchmark cases were defined as recipients with model of end-stage liver disease score Results Out of 1110 reLT 413 (37.2%) qualified as benchmark cases. Benchmark values included: Length of intensive care unit and hospital stay: =3a complications and the CCI at 1 year: Conclusion ReLT remains associated with high morbidity and mortality. The availability of benchmark values for outcome parameters of reLT may serve for comparison in any future analyses of individuals, patient groups, or centers, but also in the evaluation of new therapeutic strategies and principles.

Details

ISSN :
00034932
Volume :
276
Database :
OpenAIRE
Journal :
Annals of Surgery
Accession number :
edsair.doi.dedup.....19e9c4c527b83fc8e386ec78e8ce0ff8
Full Text :
https://doi.org/10.1097/sla.0000000000005634