Back to Search Start Over

Figure S4 from Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner

Authors :
Hans Christian Reinhardt
Sven Perner
David Maintz
Thorsten Persigehl
Jürgen Thomale
Björn Schumacher
Reinhard Büttner
Jürgen Wolf
Martin Erkel
Michael Nowak
Mehmet Deniz Akyuz
Daniela Welcker
Alexandra Florin
Luka Ozretić
Sebastian Michels
Maike Wittersheim
Arina Riabinska
Anna Schmitt
Christian Fritz
Christiane Kümpers
Anne Offermann
Wenzel Vogel
Judith Spiro
Niklas Klümper
Miriam Rinneburger
Ignacija Vlašić
Mladen Jokić
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

S4. (a) Representative immunostaining of Pt-(GpG) adducts in KP and KPE cell lines after cisplatin exposure (left). Quantification of Pt-(GpG) adduct staining in KP (n = 5) and KPE (n = 6) cells after cisplatin exposure (right). P values were calculated using two-tailed t-test. (b) Clonogenic survival assay of mock-treated KP and cisplatin-treated KP cells, mock-treated KPE and cisplatin-treated KPE cells, mock-treated KPE post cis and cisplatin-treated KPE post cis cells, mock-treated KPE post cis clone 6 (*6) and cisplatin-treated KPE post cis clone 6 (*6). (c) Detailed representation of Fig. 4c.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....1a0411eef9f13345c6fc1b494a373dda
Full Text :
https://doi.org/10.1158/1541-7786.22515120.v1