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The microbiota-mediated dietary and nutritional interventions for COVID-19
The microbiota-mediated dietary and nutritional interventions for COVID-19
- Source :
- Clinical Immunology (Orlando, Fla.)
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Worldwide, scientists are looking for specific treatment for COVID-19. Apart from the antiviral approach, the interventions to support healthy immune responses to the virus are feasible through diet, nutrition, and lifestyle approaches. This narrative review explores the recent studies on dietary, nutritional, and lifestyle interventions that influence the microbiota-mediated immunomodulatory effects against viral infections. Cumulative studies reported that the airway microbiota and SARS-CoV-2 leverage each other and determine the pathogen-microbiota-host responses. Cigarette smoking can disrupt microbiota abundance. The composition and diversification of intestinal microbiota influence the airway microbiota and the innate and adaptive immunity, which require supports from the balance of macro- and micronutrients from the diet. Colorful vegetables supplied fermentable prebiotics and anti-inflammatory, antioxidant phytonutrients. Fermented foods and beverages support intestinal microbiota. In sensitive individuals, the avoidance of the high immunoreactive food antigens contributes to antiviral immunity. This review suggests associations between airway and intestinal microbiota, antiviral host immunity, and the influences of dietary, nutritional, and lifestyle interventions to prevent the clinical course toward severe COVID-19.
- Subjects :
- 0301 basic medicine
Coronavirus disease 2019 (COVID-19)
Diet therapy
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Immunology
Anti-Inflammatory Agents
Psychological intervention
Review Article
Adaptive Immunity
digestive system
Antioxidants
03 medical and health sciences
0302 clinical medicine
Immune system
Nutritional Interventions
Gut-lung axis
Humans
Immunology and Allergy
Medicine
Life Style
Lung
Host Microbial Interactions
SARS-CoV-2
business.industry
Microbiota
Probiotics
COVID-19
Micronutrient
Acquired immune system
Immunity, Innate
Gastrointestinal Microbiome
stomatognathic diseases
Prebiotics
030104 developmental biology
business
030215 immunology
Subjects
Details
- ISSN :
- 15216616
- Volume :
- 226
- Database :
- OpenAIRE
- Journal :
- Clinical Immunology
- Accession number :
- edsair.doi.dedup.....1a264dbb751e0d38b607a9f263606f0e
- Full Text :
- https://doi.org/10.1016/j.clim.2021.108725