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The microbiota-mediated dietary and nutritional interventions for COVID-19

The microbiota-mediated dietary and nutritional interventions for COVID-19

Authors :
Asma Gasmi Benahmed
Maryam Dadar
Massimiliano Francesco Peana
Torsak Tippairote
Geir Bjørklund
Alain Menzel
Pavan Kumar Mujawdiya
Amin Gasmi
Source :
Clinical Immunology (Orlando, Fla.)
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

Worldwide, scientists are looking for specific treatment for COVID-19. Apart from the antiviral approach, the interventions to support healthy immune responses to the virus are feasible through diet, nutrition, and lifestyle approaches. This narrative review explores the recent studies on dietary, nutritional, and lifestyle interventions that influence the microbiota-mediated immunomodulatory effects against viral infections. Cumulative studies reported that the airway microbiota and SARS-CoV-2 leverage each other and determine the pathogen-microbiota-host responses. Cigarette smoking can disrupt microbiota abundance. The composition and diversification of intestinal microbiota influence the airway microbiota and the innate and adaptive immunity, which require supports from the balance of macro- and micronutrients from the diet. Colorful vegetables supplied fermentable prebiotics and anti-inflammatory, antioxidant phytonutrients. Fermented foods and beverages support intestinal microbiota. In sensitive individuals, the avoidance of the high immunoreactive food antigens contributes to antiviral immunity. This review suggests associations between airway and intestinal microbiota, antiviral host immunity, and the influences of dietary, nutritional, and lifestyle interventions to prevent the clinical course toward severe COVID-19.

Details

ISSN :
15216616
Volume :
226
Database :
OpenAIRE
Journal :
Clinical Immunology
Accession number :
edsair.doi.dedup.....1a264dbb751e0d38b607a9f263606f0e
Full Text :
https://doi.org/10.1016/j.clim.2021.108725