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WormBase: better software, richer content
- Source :
- Nucleic Acids Research
- Publication Year :
- 2006
- Publisher :
- Oxford University Press, 2006.
-
Abstract
- WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.
- Subjects :
- DNA, Complementary
Genomics
Genome browser
Computational biology
Polymorphism, Single Nucleotide
Article
User-Computer Interface
03 medical and health sciences
Software portability
0302 clinical medicine
Databases, Genetic
Genetics
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Gene
030304 developmental biology
Expressed Sequence Tags
Genome, Helminth
Internet
0303 health sciences
Expressed sequence tag
biology
biology.organism_classification
Data structure
ComputingMethodologies_PATTERNRECOGNITION
RNA Interference
WormBase
Software
030217 neurology & neurosurgery
Caltech Library Services
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Nucleic Acids Research
- Accession number :
- edsair.doi.dedup.....1aff0068b29cef2fca353fe2189e815a