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WormBase: better software, richer content

Authors :
Paul Davis
Juancarlos Chan
William Spooner
Erich M. Schwarz
Todd W. Harris
Tamberlyn Bieri
Raymond Lee
Nansheng Chen
Lincoln Stein
Carol Bastiani
Daniel Wang
Phil Ozersky
John Spieth
Hans-Michael Müller
Daniel Lawson
Tristan J. Fiedler
Richard Durbin
Andrei Petcherski
Mary Ann Tuli
Kimberly Van Auken
Paul W. Sternberg
Ranjana Kishore
Payan Canaran
Igor Antoshechkin
Lisa-Christine Girard
Anthony Rogers
Eimear E. Kenny
Wen J. Chen
Cecilia Nakamura
Darin Blasiar
Source :
Nucleic Acids Research
Publication Year :
2006
Publisher :
Oxford University Press, 2006.

Abstract

WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.

Details

Language :
English
Database :
OpenAIRE
Journal :
Nucleic Acids Research
Accession number :
edsair.doi.dedup.....1aff0068b29cef2fca353fe2189e815a